Noninvasive in-vivo optical properties of skin tumors

Alejandro Garcia-Uribe; Elizabeth B. Smith; Jun Zou; Madeleine Duvic; Lihong V. Wang

doi:10.1117/12.808397

Noninvasive in-vivo optical properties of skin tumors

Alejandro Garcia-Uribe, Elizabeth B. Smith, Jun Zou, Madeleine Duvic, Lihong V. Wang

Dermatology

Research output: Contribution to journal › Conference article › peer-review

1 Scopus citations

Abstract

This paper presents a study for in-vivo estimation of optical properties of pigmented skin tumor by oblique incidence diffuse reflectance spectroscopy. The developed system has been tested in clinical conditions to compare the optical properties of melanomas, dysplastic nevi and common nevi. The spatio-spectral data are collected in the wavelength range of 455 to 765 nm from 96 pigmented skin lesions including 10 histopathologically diagnosed as melanoma, 67 as dysplastic nevi and 19 lesions as common nevi. The preliminary results indicate significantly larger average reduced scattering coefficient spectra for malignant and dysplastic lesions than for benign common nevi.

Original language	English (US)
Article number	717506
Journal	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	7175
DOIs	https://doi.org/10.1117/12.808397
State	Published - 2009
Event	Optical Interactions with Tissue and Cells XX - San Jose, CA, United States Duration: Jan 26 2009 → Jan 28 2009

Keywords

Absorption coefficient
Melanoma
Scattering coefficient
Skin cancer
Spectroscopy

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Biomaterials
Atomic and Molecular Physics, and Optics
Radiology Nuclear Medicine and imaging

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10.1117/12.808397

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title = "Noninvasive in-vivo optical properties of skin tumors",

abstract = "This paper presents a study for in-vivo estimation of optical properties of pigmented skin tumor by oblique incidence diffuse reflectance spectroscopy. The developed system has been tested in clinical conditions to compare the optical properties of melanomas, dysplastic nevi and common nevi. The spatio-spectral data are collected in the wavelength range of 455 to 765 nm from 96 pigmented skin lesions including 10 histopathologically diagnosed as melanoma, 67 as dysplastic nevi and 19 lesions as common nevi. The preliminary results indicate significantly larger average reduced scattering coefficient spectra for malignant and dysplastic lesions than for benign common nevi.",

keywords = "Absorption coefficient, Melanoma, Scattering coefficient, Skin cancer, Spectroscopy",

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TY - JOUR

T1 - Noninvasive in-vivo optical properties of skin tumors

AU - Garcia-Uribe, Alejandro

AU - Smith, Elizabeth B.

AU - Zou, Jun

AU - Duvic, Madeleine

AU - Wang, Lihong V.

PY - 2009

Y1 - 2009

N2 - This paper presents a study for in-vivo estimation of optical properties of pigmented skin tumor by oblique incidence diffuse reflectance spectroscopy. The developed system has been tested in clinical conditions to compare the optical properties of melanomas, dysplastic nevi and common nevi. The spatio-spectral data are collected in the wavelength range of 455 to 765 nm from 96 pigmented skin lesions including 10 histopathologically diagnosed as melanoma, 67 as dysplastic nevi and 19 lesions as common nevi. The preliminary results indicate significantly larger average reduced scattering coefficient spectra for malignant and dysplastic lesions than for benign common nevi.

AB - This paper presents a study for in-vivo estimation of optical properties of pigmented skin tumor by oblique incidence diffuse reflectance spectroscopy. The developed system has been tested in clinical conditions to compare the optical properties of melanomas, dysplastic nevi and common nevi. The spatio-spectral data are collected in the wavelength range of 455 to 765 nm from 96 pigmented skin lesions including 10 histopathologically diagnosed as melanoma, 67 as dysplastic nevi and 19 lesions as common nevi. The preliminary results indicate significantly larger average reduced scattering coefficient spectra for malignant and dysplastic lesions than for benign common nevi.

KW - Absorption coefficient

KW - Melanoma

KW - Scattering coefficient

KW - Skin cancer

KW - Spectroscopy

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M3 - Conference article

AN - SCOPUS:65349107233

SN - 1605-7422

VL - 7175

JO - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

JF - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

M1 - 717506

T2 - Optical Interactions with Tissue and Cells XX

Y2 - 26 January 2009 through 28 January 2009

ER -

Noninvasive in-vivo optical properties of skin tumors

Abstract

Keywords

ASJC Scopus subject areas

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