Novel immune-based treatment strategies for chronic lymphocytic leukemia

William G. Wierda, Thomas J. Kipps, Michael J. Keating

Research output: Contribution to journalReview articlepeer-review

59 Scopus citations

Abstract

Immune-based treatments represent a new group of therapeutic strategies for patients with cancer, including chronic lymphocytic leukemia (CLL), that employ immune effector mechanisms. Among these strategies is passive immunotherapy with monoclonal antibody, alone or in combination with chemotherapy. Active immunotherapy strategies currently under development include vaccines, administration of expanded and activated T cells, and allogeneic stem cell transplantation. These immune-based strategies represent new treatments with potentially complementary mechanisms of action to standard therapies and signify major advances in treatments for patients with CLL.

Original languageEnglish (US)
Pages (from-to)6325-6332
Number of pages8
JournalJournal of Clinical Oncology
Volume23
Issue number26
DOIs
StatePublished - 2005

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Fingerprint

Dive into the research topics of 'Novel immune-based treatment strategies for chronic lymphocytic leukemia'. Together they form a unique fingerprint.

Cite this