Regiones del organizador nucleolar y patrón de ploidía del ADN en el cáncer gástrico.

Ivan Roa; J. C. Araya; Xabier de Aretxabala; I. Wistuba; M. Villaseca

Regiones del organizador nucleolar y patrón de ploidía del ADN en el cáncer gástrico.

Translated title of the contribution: Nucleolus organizer regions and ploidy pattern of DNA in stomach neoplasms

Ivan Roa
, J. C. Araya
, Xabier de Aretxabala
, I. Wistuba
, M. Villaseca

Research output: Contribution to journal › Article › peer-review

Abstract

We studied 20 gastric adenocarcinoma to determine DNA ploidy pattern by flow cytometry and nucleolar organizer regions by the colloidal silver method. There were 12 diffuse and 8 intestinal type lesions. 11 tumors were classified as diploid and 9 as aneuploid. No correlation was observed between DNA ploidy pattern and mean number of nucleolar organizer regions. The histologic type was significantly related to the number of nucleolar organizer regions (p < 0.01). Poorly differentiated lesions had significantly less nucleolar organizer regions than intestinal type lesions. Lesions with ring cells (n = 6) had similar number of nucleolar organizer regions than poorly differentiated lesions.

Translated title of the contribution	Nucleolus organizer regions and ploidy pattern of DNA in stomach neoplasms
Original language	Spanish
Pages (from-to)	647-651
Number of pages	5
Journal	Revista médica de Chile
Volume	119
Issue number	6
State	Published - Jun 1991

ASJC Scopus subject areas

General Medicine

Cite this

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title = "Regiones del organizador nucleolar y patr{\'o}n de ploid{\'i}a del ADN en el c{\'a}ncer g{\'a}strico.",

abstract = "We studied 20 gastric adenocarcinoma to determine DNA ploidy pattern by flow cytometry and nucleolar organizer regions by the colloidal silver method. There were 12 diffuse and 8 intestinal type lesions. 11 tumors were classified as diploid and 9 as aneuploid. No correlation was observed between DNA ploidy pattern and mean number of nucleolar organizer regions. The histologic type was significantly related to the number of nucleolar organizer regions (p < 0.01). Poorly differentiated lesions had significantly less nucleolar organizer regions than intestinal type lesions. Lesions with ring cells (n = 6) had similar number of nucleolar organizer regions than poorly differentiated lesions.",

author = "Ivan Roa and Araya, \{J. C.\} and \{de Aretxabala\}, Xabier and I. Wistuba and M. Villaseca",

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year = "1991",

month = jun,

language = "Spanish",

volume = "119",

pages = "647--651",

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T1 - Regiones del organizador nucleolar y patrón de ploidía del ADN en el cáncer gástrico.

AU - Roa, Ivan

AU - Araya, J. C.

AU - de Aretxabala, Xabier

AU - Wistuba, I.

AU - Villaseca, M.

N1 - Copyright: This record is sourced from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

PY - 1991/6

Y1 - 1991/6

N2 - We studied 20 gastric adenocarcinoma to determine DNA ploidy pattern by flow cytometry and nucleolar organizer regions by the colloidal silver method. There were 12 diffuse and 8 intestinal type lesions. 11 tumors were classified as diploid and 9 as aneuploid. No correlation was observed between DNA ploidy pattern and mean number of nucleolar organizer regions. The histologic type was significantly related to the number of nucleolar organizer regions (p < 0.01). Poorly differentiated lesions had significantly less nucleolar organizer regions than intestinal type lesions. Lesions with ring cells (n = 6) had similar number of nucleolar organizer regions than poorly differentiated lesions.

AB - We studied 20 gastric adenocarcinoma to determine DNA ploidy pattern by flow cytometry and nucleolar organizer regions by the colloidal silver method. There were 12 diffuse and 8 intestinal type lesions. 11 tumors were classified as diploid and 9 as aneuploid. No correlation was observed between DNA ploidy pattern and mean number of nucleolar organizer regions. The histologic type was significantly related to the number of nucleolar organizer regions (p < 0.01). Poorly differentiated lesions had significantly less nucleolar organizer regions than intestinal type lesions. Lesions with ring cells (n = 6) had similar number of nucleolar organizer regions than poorly differentiated lesions.

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M3 - Article

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AN - SCOPUS:0026174439

SN - 0034-9887

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SP - 647

EP - 651

JO - Revista médica de Chile

JF - Revista médica de Chile

IS - 6

ER -

Regiones del organizador nucleolar y patrón de ploidía del ADN en el cáncer gástrico.

Abstract

ASJC Scopus subject areas

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