Obesity and male breast cancer: Provocative parallels?

Matthew P. Humphries, V. Craig Jordan, Valerie Speirs

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

While rare compared to female breast cancer the incidence of male breast cancer (MBC) has increased in the last few decades. Without comprehensive epidemiological studies, the explanation for the increased incidence of MBC can only be speculated. Nevertheless, one of the most worrying global public health issues is the exponential rise in the number of overweight and obese people, especially in the developed world. Although obesity is not considered an established risk factor for MBC, studies have shown increased incidence among obese individuals. With this observation in mind, this article highlights the correlation between the increased incidence of MBC and the current trends in obesity as a growing problem in the 21st century, including how this may impact treatment. With MBC becoming more prominent we put forward the notion that, not only is obesity a risk factor for MBC, but that increasing obesity trends are a contributing factor to its increased incidence.

Original languageEnglish (US)
Article number134
JournalBMC medicine
Volume13
Issue number1
DOIs
StatePublished - Jun 4 2015

Keywords

  • Aromatase
  • Aromatase inhibitor
  • Body mass index
  • Estrogen
  • Incidence
  • Male breast cancer
  • Obesity
  • Risk factor
  • Selective estrogen receptor modulator
  • Tamoxifen

ASJC Scopus subject areas

  • General Medicine

Fingerprint

Dive into the research topics of 'Obesity and male breast cancer: Provocative parallels?'. Together they form a unique fingerprint.

Cite this