Oblique-incidence spatially resolved diffuse reflectance spectroscopic diagnosis of skin cancer

Alejandro Garcia-Uribe, Jun Zou, Tzu Hsuan Chang, Madeleine Duvic, Victor Prieto, Lihong V. Wang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Abstract

This paper presents the use of spatially resolved oblique-incidence diffuse reflectance spectroscopy for skin cancer diagnosis. Spatio-spectral data from 166 pigmented skin lesions were collected for the wavelength range from 455 to 765 nm. A set of neural network based classifiers separates the pigmented malignant melanomas from the benign and dysplastic subgroups. A total of 110 lesions were used as the training set and 56 lesions were used as the testing set. This classifier performs with an overall 100% sensitivity and 92% specificity for the training set and 100% sensitivity and 88% specificity for the testing set. The second classifier was designed to separate the benign from the dysplastic subgroups. For the second classifier a total of 100 lesions were used as the training set and 51 lesions were used as the testing set. The overall classification rates were 94% and 88% for the training and testing sets respectively.

Original languageEnglish (US)
Title of host publicationOptical Diagnostics and Sensing X
Subtitle of host publicationToward Point-of-Care Diagnostics
PublisherSPIE
ISBN (Print)9780819479686
DOIs
StatePublished - Feb 11 2010
EventOptical Diagnostics and Sensing X: Toward Point-of-Care Diagnostics - San Francisco, CA, United States
Duration: Jan 25 2010Jan 26 2010

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7572
ISSN (Print)1605-7422

Other

OtherOptical Diagnostics and Sensing X: Toward Point-of-Care Diagnostics
Country/TerritoryUnited States
CitySan Francisco, CA
Period1/25/101/26/10

Keywords

  • Diffuse reflectance
  • Melanoma
  • Skin cancer
  • Spectroscopy

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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