Abstract
Alcohol-dependent outpatients with persisting insomnia were treated with either gabapentin or trazodone. Patients were assessed at baseline and after 4-6 weeks on medication using the Sleep Problems Questionnaire (SPQ). Of 55 cases initially treated, 9% dropped out due to morning drowsiness. Of the remaining 50 cases, 34 were treated with gabapentin (mean dose± SD=888±418mg) at bedtime and 16 were treated with trazodone (105±57mg) at bedtime. Both groups improved significantly on the SPQ but the gabapentin group improved significantly more than the trazodone group. Controlled studies are warranted to replicate these findings.
Original language | English (US) |
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Pages (from-to) | 542-544 |
Number of pages | 3 |
Journal | Psychiatry and Clinical Neurosciences |
Volume | 57 |
Issue number | 5 |
DOIs | |
State | Published - Oct 2003 |
Externally published | Yes |
Keywords
- Alcoholism
- Drug therapy
- Gabapentin
- Insomnia
- Trazodone
ASJC Scopus subject areas
- General Neuroscience
- Neurology
- Clinical Neurology
- Psychiatry and Mental health