Optimal size and PEG coating of gold nanoparticles for prolonged blood circulation: a statistical analysis of published data

Dmitry Nevozhay; Ronald Rauch; Zhongya Wang; Konstantin V. Sokolov

doi:10.1039/d4na00782d

Optimal size and PEG coating of gold nanoparticles for prolonged blood circulation: a statistical analysis of published data

Dmitry Nevozhay, Ronald Rauch, Zhongya Wang, Konstantin V. Sokolov

Research output: Contribution to journal › Article › peer-review

Abstract

This study presents a statistical analysis of how gold nanoparticle (GNP) size and polyethylene glycol (PEG) coating molecular weight (MW) affect the circulation of nanoparticles in blood. We showed a non-linear relationship with interaction between GNP size and PEG MW. The findings revealed a threshold effect, and recommendations for GNP coating are discussed.

Original language	English (US)
Pages (from-to)	722-727
Number of pages	6
Journal	Nanoscale Advances
Volume	7
Issue number	3
DOIs	https://doi.org/10.1039/d4na00782d
State	Published - Jan 13 2025

ASJC Scopus subject areas

Bioengineering
Atomic and Molecular Physics, and Optics
General Chemistry
General Materials Science
General Engineering

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10.1039/d4na00782d

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abstract = "This study presents a statistical analysis of how gold nanoparticle (GNP) size and polyethylene glycol (PEG) coating molecular weight (MW) affect the circulation of nanoparticles in blood. We showed a non-linear relationship with interaction between GNP size and PEG MW. The findings revealed a threshold effect, and recommendations for GNP coating are discussed.",

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Optimal size and PEG coating of gold nanoparticles for prolonged blood circulation: a statistical analysis of published data

Abstract

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