TY - JOUR
T1 - Oral pain associated with cancer therapy, a pain medicine perspective
AU - Roldan, Carlos J.
AU - Chai, Thomas
AU - Erian, Jennifer
AU - Welker, John
N1 - Publisher Copyright:
© 2018 Future Medicine Ltd.
PY - 2018
Y1 - 2018
N2 - Cancer therapy-induced oral mucositis (CTIOM) can cause intolerable oral pain resulting in difficulty in chewing, swallowing and speaking. Thus, leading to patients requiring aggressive measures, such as parenteral feeding, the placement of gastric feeding tubes and discontinuation of oncologic treatments. Although, pain is the debilitating symptom, current efforts seem to focus independently in the histological damage, not in pain and symptom care. Current strategies for managing pain from CTIOM entail maintaining oral hygiene and the use of oral rinses, topical anesthetics, prophylactic antimicrobials and systemic analgesics such as opioids. Novel therapies, such as methylene blue oral rinse, are being investigated, with positive outcomes. Therefore, there is a need to identify treatment modalities for pain of CTIOM. Ideally, this should be noninvasive, safe and cost-effective, while providing sustained analgesia.
AB - Cancer therapy-induced oral mucositis (CTIOM) can cause intolerable oral pain resulting in difficulty in chewing, swallowing and speaking. Thus, leading to patients requiring aggressive measures, such as parenteral feeding, the placement of gastric feeding tubes and discontinuation of oncologic treatments. Although, pain is the debilitating symptom, current efforts seem to focus independently in the histological damage, not in pain and symptom care. Current strategies for managing pain from CTIOM entail maintaining oral hygiene and the use of oral rinses, topical anesthetics, prophylactic antimicrobials and systemic analgesics such as opioids. Novel therapies, such as methylene blue oral rinse, are being investigated, with positive outcomes. Therefore, there is a need to identify treatment modalities for pain of CTIOM. Ideally, this should be noninvasive, safe and cost-effective, while providing sustained analgesia.
KW - oral pain
KW - cancer therapy-induced oral mucositis
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U2 - 10.2217/pmt-2018-0036
DO - 10.2217/pmt-2018-0036
M3 - Review article
C2 - 30411665
AN - SCOPUS:85056984603
SN - 1758-1869
VL - 8
SP - 487
EP - 493
JO - Pain management
JF - Pain management
IS - 6
ER -