Abstract
Advanced Glycation End-products (AGEs) are the products of non-enzymatic glycation protein. It has been demonstrated that AGEs are closely correlated to a variety of diseases such as diabetes, vascular complications, aging and renal diseases, AGEs play important roles in the development of these diseases. They can effect the function of cells and tissues directly, and also mediate pathological reactions through binding with special receptors. The present paper reviews the procedures of AGEs production, action mechanism and pathology of AGEs.
Original language | English (US) |
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Pages (from-to) | 246-249 |
Number of pages | 4 |
Journal | Chinese Pharmacological Bulletin |
Volume | 18 |
Issue number | 3 |
State | Published - 2002 |
Externally published | Yes |
Keywords
- AGEs
- Aging
- Diabetes
- Maillard reaction
ASJC Scopus subject areas
- Pharmacology