Persistent mitosis of transfused homologous leukocytes in children receiving antileukemic therapy

Robert H. Levin, Jacqueline Whang, J. H. Tjio, Paul P. Carbone, Emil Frei, Emil J. Freireich

Research output: Contribution to journalArticlepeer-review

41 Scopus citations

Abstract

Temporary homologous bone marrow grafts were observed in three patients with acute leukemia, receiving intensive antileukemic treatment, following transfusion of peripheral blood cells from donors with chronic myelocytic leukemia. Persistent mitosis of the transfused cells, containing the Philadelphia chromosome marker, were detected by cytogenetic techniques 19, 39, and 52 days after transfusion.

Original languageEnglish (US)
Pages (from-to)1311-1313
Number of pages3
JournalScience
Volume142
Issue number3597
DOIs
StatePublished - 1963

ASJC Scopus subject areas

  • General

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