Personalized Medicine: Patient-Predictive Panel Power

Paul Workman, Paul A. Clarke, Bissan Al-Lazikani

Research output: Contribution to journalShort surveypeer-review

13 Scopus citations

Abstract

Two recent papers published in Nature demonstrate the power of systematic high-throughput pharmacologic profiling of very large, diverse, molecularly-characterized human cancer cell line panels to reveal linkages between genetic profile and targeted-drug sensitivity. Known oncogene addictions are confirmed while surprising complexities and biomarker relationships with clinical potential are revealed.

Original languageEnglish (US)
Pages (from-to)455-458
Number of pages4
JournalCancer cell
Volume21
Issue number4
DOIs
StatePublished - Apr 17 2012
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cell Biology
  • Cancer Research

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