Production of 61CU by deuteron irradiation of natural NI

Roberto Strangis; Carlos Gonzalez Lepera

Production of ⁶¹CU by deuteron irradiation of natural NI

Roberto Strangis, Carlos Gonzalez Lepera

Nuclear Medicine

Research output: Contribution to conference › Paper › peer-review

3 Scopus citations

Abstract

⁶¹Cu (T1/2=3.33h, 61% β⁺) offers several advantages over other Cu radioisotopes for labeling radiopharmaceuticals for positron emission tomography (PET). Production of ⁶¹Cu[CuCl ₂] for distribution to biomedical research facilities has been performed at Cyclotope since 2003. Using the ^natNi(d,x) ⁶¹Cu reaction, high purity (99%+) natural nickel plates mounted on the solid target beam line of our TR19/9 cyclotron were irradiated. In order to significantly increase the production capacity of this radiotracer for future human studies in a cost efficient manner we optimized the existing beam line and solid target station. In addition, a remote chemical processing unit was constructed to dissolve the irradiated plates and separate ⁶¹Cu from the Ni matrix and other radionuclide impurities. Target saturation yields, processing method and final product characteristics are described in this presentation.

Original language	English (US)
Pages	246-247
Number of pages	2
State	Published - 2007
Event	18th International Conference on Cyclotrons and Their Applications 2007, CYCLOTRONS 2007 - Giardini Naxos, Italy Duration: Oct 1 2007 → Oct 5 2007

Other

Other	18th International Conference on Cyclotrons and Their Applications 2007, CYCLOTRONS 2007
Country/Territory	Italy
City	Giardini Naxos
Period	10/1/07 → 10/5/07

ASJC Scopus subject areas

Atomic and Molecular Physics, and Optics

Cite this

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title = "Production of 61CU by deuteron irradiation of natural NI",

abstract = "61Cu (T1/2=3.33h, 61% β+) offers several advantages over other Cu radioisotopes for labeling radiopharmaceuticals for positron emission tomography (PET). Production of 61Cu[CuCl 2] for distribution to biomedical research facilities has been performed at Cyclotope since 2003. Using the natNi(d,x) 61Cu reaction, high purity (99%+) natural nickel plates mounted on the solid target beam line of our TR19/9 cyclotron were irradiated. In order to significantly increase the production capacity of this radiotracer for future human studies in a cost efficient manner we optimized the existing beam line and solid target station. In addition, a remote chemical processing unit was constructed to dissolve the irradiated plates and separate 61Cu from the Ni matrix and other radionuclide impurities. Target saturation yields, processing method and final product characteristics are described in this presentation.",

author = "Roberto Strangis and Lepera, {Carlos Gonzalez}",

note = "Copyright: Copyright 2013 Elsevier B.V., All rights reserved.; 18th International Conference on Cyclotrons and Their Applications 2007, CYCLOTRONS 2007 ; Conference date: 01-10-2007 Through 05-10-2007",

year = "2007",

language = "English (US)",

pages = "246--247",

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T1 - Production of 61CU by deuteron irradiation of natural NI

AU - Strangis, Roberto

AU - Lepera, Carlos Gonzalez

PY - 2007

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N2 - 61Cu (T1/2=3.33h, 61% β+) offers several advantages over other Cu radioisotopes for labeling radiopharmaceuticals for positron emission tomography (PET). Production of 61Cu[CuCl 2] for distribution to biomedical research facilities has been performed at Cyclotope since 2003. Using the natNi(d,x) 61Cu reaction, high purity (99%+) natural nickel plates mounted on the solid target beam line of our TR19/9 cyclotron were irradiated. In order to significantly increase the production capacity of this radiotracer for future human studies in a cost efficient manner we optimized the existing beam line and solid target station. In addition, a remote chemical processing unit was constructed to dissolve the irradiated plates and separate 61Cu from the Ni matrix and other radionuclide impurities. Target saturation yields, processing method and final product characteristics are described in this presentation.

AB - 61Cu (T1/2=3.33h, 61% β+) offers several advantages over other Cu radioisotopes for labeling radiopharmaceuticals for positron emission tomography (PET). Production of 61Cu[CuCl 2] for distribution to biomedical research facilities has been performed at Cyclotope since 2003. Using the natNi(d,x) 61Cu reaction, high purity (99%+) natural nickel plates mounted on the solid target beam line of our TR19/9 cyclotron were irradiated. In order to significantly increase the production capacity of this radiotracer for future human studies in a cost efficient manner we optimized the existing beam line and solid target station. In addition, a remote chemical processing unit was constructed to dissolve the irradiated plates and separate 61Cu from the Ni matrix and other radionuclide impurities. Target saturation yields, processing method and final product characteristics are described in this presentation.

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T2 - 18th International Conference on Cyclotrons and Their Applications 2007, CYCLOTRONS 2007

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ER -

Production of ⁶¹CU by deuteron irradiation of natural NI

Abstract

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ASJC Scopus subject areas

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