Prognostic and Predictive Factors of Invasive Breast Cancer

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Abstract

Invasive breast carcinomas comprise a heterogeneous group of lesions that differ in their molecular and pathologic features and clinical behavior. Some patients have long disease-free survival, whereas others experience the rapid development of recurrence and metastases that are fatal within a few years of the initial diagnosis. Many factors in individual tumors can be evaluated to stratify patients into subsets with varying risks of recurrence and response to different therapy modalities. This chapter describes the current standard prognostic and predictive factors of invasive breast carcinoma and discusses emerging data on molecular markers which can be considered in clinical practice.

Original languageEnglish (US)
Title of host publicationBreast Disease
Subtitle of host publicationDiagnosis and Pathology
PublisherSpringer International Publishing
Pages187-206
Number of pages20
Volume1
ISBN (Electronic)9783319228433
ISBN (Print)9783319228426
DOIs
StatePublished - Jan 1 2015

Keywords

  • Estrogen and progesterone receptors
  • Her2/neu
  • Histopathology
  • Invasive breast cancer
  • Prognostic factors
  • Tumor biomarkers

ASJC Scopus subject areas

  • General Medicine
  • General Biochemistry, Genetics and Molecular Biology

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