Abstract
Invasive breast carcinomas comprise a heterogeneous group of lesions that differ in their molecular and pathologic features and clinical behavior. Some patients have long disease-free survival, whereas others experience the rapid development of recurrence and metastases that are fatal within a few years of the initial diagnosis. Many factors in individual tumors can be evaluated to stratify patients into subsets with varying risks of recurrence and response to different therapy modalities. This chapter describes the current standard prognostic and predictive factors of invasive breast carcinoma and discusses emerging data on molecular markers which can be considered in clinical practice.
Original language | English (US) |
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Title of host publication | Breast Disease |
Subtitle of host publication | Diagnosis and Pathology |
Publisher | Springer International Publishing |
Pages | 187-206 |
Number of pages | 20 |
Volume | 1 |
ISBN (Electronic) | 9783319228433 |
ISBN (Print) | 9783319228426 |
DOIs | |
State | Published - Jan 1 2015 |
Keywords
- Estrogen and progesterone receptors
- Her2/neu
- Histopathology
- Invasive breast cancer
- Prognostic factors
- Tumor biomarkers
ASJC Scopus subject areas
- General Medicine
- General Biochemistry, Genetics and Molecular Biology