Proteomic global profiling for cancer biomarker discovery.

Vitor Faca; Hong Wang; Samir Hanash

doi:10.1007/978-1-59745-493-3_19

Proteomic global profiling for cancer biomarker discovery.

Vitor Faca
, Hong Wang
, Samir Hanash

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

The ultimate goal of cancer molecular diagnostics is the development of simple tests to predict cancer risk, detect cancer early, classify tumors, and monitor response to therapy. Proteomics is well suited for these tasks. However, there are substantial challenges that need to be met to identify the most informative markers using proteomics. Approaches for in-depth quantitative proteomic analysis based on isotopic labeling and protein fractionation are presented in this chapter.

Original language	English (US)
Pages (from-to)	309-320
Number of pages	12
Journal	Methods in molecular biology (Clifton, N.J.)
Volume	492
DOIs	https://doi.org/10.1007/978-1-59745-493-3_19
State	Published - 2009
Externally published	Yes

ASJC Scopus subject areas

Molecular Biology
Genetics

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10.1007/978-1-59745-493-3_19

Cite this

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title = "Proteomic global profiling for cancer biomarker discovery.",

abstract = "The ultimate goal of cancer molecular diagnostics is the development of simple tests to predict cancer risk, detect cancer early, classify tumors, and monitor response to therapy. Proteomics is well suited for these tasks. However, there are substantial challenges that need to be met to identify the most informative markers using proteomics. Approaches for in-depth quantitative proteomic analysis based on isotopic labeling and protein fractionation are presented in this chapter.",

author = "Vitor Faca and Hong Wang and Samir Hanash",

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AU - Wang, Hong

AU - Hanash, Samir

PY - 2009

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AB - The ultimate goal of cancer molecular diagnostics is the development of simple tests to predict cancer risk, detect cancer early, classify tumors, and monitor response to therapy. Proteomics is well suited for these tasks. However, there are substantial challenges that need to be met to identify the most informative markers using proteomics. Approaches for in-depth quantitative proteomic analysis based on isotopic labeling and protein fractionation are presented in this chapter.

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UR - https://www.scopus.com/pages/publications/62349086621#tab=citedBy

U2 - 10.1007/978-1-59745-493-3_19

DO - 10.1007/978-1-59745-493-3_19

M3 - Article

C2 - 19241042

AN - SCOPUS:62349086621

SN - 1064-3745

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JO - Methods in molecular biology (Clifton, N.J.)

JF - Methods in molecular biology (Clifton, N.J.)

ER -

Proteomic global profiling for cancer biomarker discovery.

Abstract

ASJC Scopus subject areas

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