Abstract
With the human genome sequence now determined, the field of molecular medicine is moving beyond genomics to proteomics. In the field of cancer research, the key question is: how can oncologists best use techniques of proteomics in basic research and clinical application? In the postgenomic era, proteomics promises the discovery of biomarkers and tumor markers for early detection and diagnosis, novel protein-based drug targets for anticancer therapy, and new endpoints for the assessment of therapeutic efficacy and toxicity. This review paper will explore key themes in proteomics and their application in clinical cancer research.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 409-423 |
| Number of pages | 15 |
| Journal | International Journal of Gynecological Cancer |
| Volume | 12 |
| Issue number | 5 |
| DOIs | |
| State | Published - Sep 2002 |
Keywords
- Cancer
- Clinical application
- Proteomics
ASJC Scopus subject areas
- Oncology
- Obstetrics and Gynecology