Rabbit Neoplasia

Peggy T. Tinkey, Rajesh K. Uthamanthil, Steven H. Weisbroth

Research output: Chapter in Book/Report/Conference proceedingChapter

23 Scopus citations

Abstract

This chapter presents new data that have been accumulated on rabbit neoplasia from case reports, descriptions of biological aspects of a variety of naturally occurring tumors, and reports of experimentally induced tumor models. Although much of the early data originated from rabbit colonies associated with major research institutions, the growing popularity of domestic rabbits as pets allows an increased ability to accumulate data on the spontaneous incidence of tumors in rabbits that are allowed to live a natural life span. Naturally occurring neoplasms in the rabbit were previously thought to be sporadic but there is evidence for a regular pattern in the incidence of the various tumor types known to be naturally associated with Oryctolagus. It is difficult to determine the actual incidence of spontaneous neoplasms in the domestic rabbit. The normal lifespan of the domestic rabbit Oryctolagus is 7–8 years, but they are used at younger ages in most research studies and breeding colonies, and are seldom maintained through their natural lifespan. Rabbits are similar to most species in that neoplasia is infrequent in juveniles and young adults.

Original languageEnglish (US)
Title of host publicationThe Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents
PublisherElsevier
Pages447-501
Number of pages55
ISBN (Electronic)9780123809209
DOIs
StatePublished - Jan 1 2012

Keywords

  • Animal model
  • Cancer
  • Hare
  • Neoplasm
  • Oncogenesis
  • Rabbit

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology

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