Radial dose distributions from carbon ions of therapeutic energies calculated with Geant4-DNA

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13 Scopus citations

Abstract

We report on radial dose distributions D(r) for carbon ions calculated with Geant4-DNA code. These distributions characterize ion tracks on a nanoscale and are important for understanding the biological effects of ion beams. We present data for carbon ion beams in the energy range from 20 to 400 MeVu-1. To approximate the Monte Carlo results, we developed a simple formula that combines the well-known inverse square distance dependence with a factor correcting D(r) for small r . The proposed formula can be used to calculate D(r) for any energy within the above range and for distances r from 1 nm to 2 μm with a maximum error not exceeding 14%. This range of distances corresponds to a dose range of over seven orders of magnitude. Differences between our results and those of previously published analytical models are discussed.

Original languageEnglish (US)
Pages (from-to)N219-N227
JournalPhysics in medicine and biology
Volume62
Issue number10
DOIs
StatePublished - Apr 20 2017

Keywords

  • amorphous track model
  • carbon ion beam therapy
  • hadron therapy
  • local effect model
  • track structure

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

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