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Radiation for inflammatory breast cancer: Updates

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Inflammatory breast cancer (IBC) is a diagnosis based on a constellation of clinical features of edema (peau d'orange) of a third or more of the skin of the breast with a palpable border and a rapid onset of breast erythema. Incidence of IBC has increased over time, although it still makes up only 1–4% of all breast cancer diagnoses. Despite recent encouraging data on clinical outcomes, the published local-regional control rates remain consistently lower than the rates for non-IBC. In this review, we focus on radiotherapy, provide a framework for multi-disciplinary care for IBC, describe local-regional treatment techniques for IBC; highlight new directions in the management of patients with metastatic IBC and offer an introduction to future directions regarding the optimal treatment and management of IBC.

Original languageEnglish (US)
Title of host publicationOverview of Inflammatory Breast Cancer
Subtitle of host publicationUpdates
EditorsMaroua Manai, Hamouda Boussen, Massimo Cristofanilli
PublisherElsevier Inc.
Pages25-46
Number of pages22
ISBN (Print)9780443133480
DOIs
StatePublished - Jan 2024

Publication series

NameInternational Review of Cell and Molecular Biology
Volume384
ISSN (Print)1937-6448

Keywords

  • Breast cancer
  • Contralateral axillary nodes
  • Dose escalation
  • IBC
  • Inflammatory breast cancer
  • Metastasis
  • Palliation
  • Radiation
  • Radiotherapy
  • Skin metastasis

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology

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