TY - JOUR
T1 - Rapid on-site evaluation of endobronchial ultrasound-guided transbronchial needle aspirations for the diagnosis of lung cancer a perspective from members of the Pulmonary Pathology Society
AU - Jain, Deepali
AU - Allen, Timothy Craig
AU - Aisner, Dara L.
AU - Beasley, Mary Beth
AU - Cagle, Philip T.
AU - Capelozzi, Vera Luiza
AU - Hariri, Lida P.
AU - Lantuejoul, Sylvie
AU - Miller, Ross
AU - Mino-Kenudson, Mari
AU - Monaco, Sara E.
AU - Moreira, Andre
AU - Raparia, Kirtee
AU - Rekhtman, Natasha
AU - Roden, Anja Christiane
AU - Roy-Chowdhuri, Sinchita
AU - Da Cunha Santos, Gilda
AU - Thunnissen, Erik
AU - Troncone, Giancarlo
AU - Vivero, Marina
N1 - Funding Information:
From the Department of Pathology, All India Institute of Medical Sciences, New Delhi, India (Dr Jain); the Department of Pathology, University of Texas Medical Branch, Galveston (Dr Allen); the Department of Pathology, University of Colorado, Aurora (Dr Aisner); the Department of Pathology, Mount Sinai Medical Center, New York, New York (Dr Beasley); the Department of Pathology & Genomic Medicine, Houston Methodist Hospital, Houston, Texas (Drs Cagle and Miller); the Department of Pathology, University of São Paulo, São Paulo, Brazil (Dr Capelozzi); the Department of Pathology, Massachusetts General Hospital, Boston (Drs Hariri and Mino-Kenudson); the Département de Biopathologie, Centre Léon Bérard, Lyon, France (Dr Lantuejoul); UniversitéJoseph Fourier INSERM U 823, Institut A. Bonniot, La Tronche, France (Dr Lantuejoul); the Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania (Dr Monaco); the Department of Pathology, New York University Langone Medical Center, New York, New York (Dr Moreira); the Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois (Dr Raparia); the Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York (Dr Rekhtman); the Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota (Dr Roden); the Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston (Dr Roy-Chowdhuri); the Department of Laboratory Medicine and Pathobiology, University of Toronto University Health Network, Toronto, Ontario, Canada (Dr Santos); the Department of Pathology, VU Medical Center, Amsterdam, the Netherlands (Dr Thunnissen); the Dipartimento di SanitàPubblica, Universitàdegli Studi di Napoli Federico II, Naples, Italy (Dr Troncone); and the Department of Pathology, Harvard Medical School and Brigham and Women’s Hospital, Boston, Massachusetts (Dr Vivero).
PY - 2018/2/1
Y1 - 2018/2/1
N2 - Context.-Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has emerged as a very useful tool in the field of diagnostic respiratory cytology. Rapid on-site evaluation (ROSE) of EBUS-TBNA not only has the potential to improve diagnostic yield of the procedure but also to triage samples for predictive molecular testing to guide personalized treatments for lung cancer. Objective.-To provide an overview of the current status of the literature regarding ROSE of EBUS-TBNA in the diagnosis of lung cancer. Data Sources.-An electronic literature search in PubMed and Google databases was performed using the following key words: cytology, lung cancer, on-site evaluation, rapid on-site evaluation, and ROSE EBUSTBNA. Only articles published in English were included in this review. Conclusions.-Rapid on-site evaluation can ensure that the targeted lesion is being sampled and can enable appropriate specimen triage. If available, it should be used with EBUS-TBNA in the diagnosis of lung cancer because it can minimize repeat procedures for additional desired testing (ie, molecular studies). Some studies have shown that ROSE does not adversely affect the number of aspirations, total procedure time of EBUS-TBNA, or the rate of postprocedure complications; it is also helpful in providing a preliminary diagnosis that can reduce the number of additional invasive procedures, such as mediastinoscopy. As EBUS technology continues to evolve, our knowledge of the role of ROSE in EBUS-TBNA for the diagnosis of lung cancer will also continue to grow and evolve.
AB - Context.-Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has emerged as a very useful tool in the field of diagnostic respiratory cytology. Rapid on-site evaluation (ROSE) of EBUS-TBNA not only has the potential to improve diagnostic yield of the procedure but also to triage samples for predictive molecular testing to guide personalized treatments for lung cancer. Objective.-To provide an overview of the current status of the literature regarding ROSE of EBUS-TBNA in the diagnosis of lung cancer. Data Sources.-An electronic literature search in PubMed and Google databases was performed using the following key words: cytology, lung cancer, on-site evaluation, rapid on-site evaluation, and ROSE EBUSTBNA. Only articles published in English were included in this review. Conclusions.-Rapid on-site evaluation can ensure that the targeted lesion is being sampled and can enable appropriate specimen triage. If available, it should be used with EBUS-TBNA in the diagnosis of lung cancer because it can minimize repeat procedures for additional desired testing (ie, molecular studies). Some studies have shown that ROSE does not adversely affect the number of aspirations, total procedure time of EBUS-TBNA, or the rate of postprocedure complications; it is also helpful in providing a preliminary diagnosis that can reduce the number of additional invasive procedures, such as mediastinoscopy. As EBUS technology continues to evolve, our knowledge of the role of ROSE in EBUS-TBNA for the diagnosis of lung cancer will also continue to grow and evolve.
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U2 - 10.5858/arpa.2017-0114-SA
DO - 10.5858/arpa.2017-0114-SA
M3 - Article
C2 - 28639854
AN - SCOPUS:85047972847
SN - 0003-9985
VL - 142
SP - 253
EP - 262
JO - Archives of Pathology and Laboratory Medicine
JF - Archives of Pathology and Laboratory Medicine
IS - 2
ER -