Recent progress in classification, markers and function of tumor-related circulating endothelial cells

Wenjing Xu, Kai Li

    Research output: Contribution to journalReview article

    Abstract

    Two major processes by which tumor blood vessels are developed and remodeled are based on the proliferation, migration, and adhesion of circulating endothelial cells (CECs). CECs therefore contribute to tumor neovasculogenesis and possibly to the progression and metastasis of tumors. CECs are possible targets for antiangiogenic therapy and predictors of treatment efficacy. In this review, we discuss the classification, markers and function of tumor-related CECs.

    Original languageEnglish (US)
    Pages (from-to)353-356
    Number of pages4
    JournalChinese Journal of Clinical Oncology
    Volume36
    Issue number6
    DOIs
    StatePublished - Dec 1 2009

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    Keywords

    • Angiogenesis
    • Circulating endothelial cells (CECs)
    • Endothelial progenitor cells (EPCs)
    • Vasculogenesis

    ASJC Scopus subject areas

    • Oncology
    • Cancer Research

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