@inproceedings{b91f341cb7a24e03a443f5678927e5e1,
title = "Reconstructing the angiome: A new platform for characterizing disease progre{\ss}ion and drug efficacy",
abstract = "A comprehensive understanding of microvascular networks is required to generate platforms that track treatment efficacy. Current approaches are labor intensive and limited to small ti{\ss}ue volumes. In this work we describe an acquisition and segmentation framework for low-cost imaging and microvascular modeling at resolution comparable to confocal with data rates comparable to light-sheet microscopy. Segmentation is performed using a GPU-based method that extracts microvascular structure and connectivity embedded in these images. The microvasculature network is stored such that the graph [G = V, E] structure can be exploited to quantify large-scale angiomes and facilitate data mining at the terabyte scale.",
keywords = "Three-dimensional microscopy",
author = "Pavel Govyadinov and Jiaming Guo and Leila Saadatifard and Camille Artur and Jason Eriksen and Guoning Chen and David Mayerich",
note = "Publisher Copyright: {\textcopyright} COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.; Design and Quality for Biomedical Technologies XIII 2020 ; Conference date: 01-02-2020 Through 03-02-2020",
year = "2020",
doi = "10.1117/12.2555137",
language = "English (US)",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
publisher = "SPIE",
editor = "Jeeseong Hwang and Gracie Vargas",
booktitle = "Design and Quality for Biomedical Technologies XIII",
}