Red blood cell storage: How long is too long?

Colleen G. Koch; Priscilla I. Figueroa; Liang Li; Joseph F. Sabik; Tomislav Mihaljevic; Eugene H. Blackstone

doi:10.1016/j.athoracsur.2013.05.116

Red blood cell storage: How long is too long?

Colleen G. Koch, Priscilla I. Figueroa, Liang Li, Joseph F. Sabik, Tomislav Mihaljevic, Eugene H. Blackstone

Research output: Contribution to journal › Review article › peer-review

58 Scopus citations

Abstract

Red blood cells (RBCs) undergo biochemical and structural changes during storage, commonly referred to as the "storage lesion." Evidence suggests that the longer the RBC product is stored, the less effective is the transfused blood. Many studies linking morbidity to transfusion have not considered duration of RBC storage as a variable that may modulate the effect. In addition, the effects of supply and demand and RBC inventory management strategies have been incompletely investigated. It is possible to envision a blood management system based on modern inventory management strategies that could greatly reduce storage duration.

Original language	English (US)
Pages (from-to)	1894-1899
Number of pages	6
Journal	Annals of Thoracic Surgery
Volume	96
Issue number	5
DOIs	https://doi.org/10.1016/j.athoracsur.2013.05.116
State	Published - Nov 2013
Externally published	Yes

ASJC Scopus subject areas

Surgery
Pulmonary and Respiratory Medicine
Cardiology and Cardiovascular Medicine

MD Anderson CCSG core facilities

Biostatistics Resource Group

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10.1016/j.athoracsur.2013.05.116

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title = "Red blood cell storage: How long is too long?",

abstract = "Red blood cells (RBCs) undergo biochemical and structural changes during storage, commonly referred to as the {"}storage lesion.{"} Evidence suggests that the longer the RBC product is stored, the less effective is the transfused blood. Many studies linking morbidity to transfusion have not considered duration of RBC storage as a variable that may modulate the effect. In addition, the effects of supply and demand and RBC inventory management strategies have been incompletely investigated. It is possible to envision a blood management system based on modern inventory management strategies that could greatly reduce storage duration.",

author = "Koch, {Colleen G.} and Figueroa, {Priscilla I.} and Liang Li and Sabik, {Joseph F.} and Tomislav Mihaljevic and Blackstone, {Eugene H.}",

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language = "English (US)",

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T2 - How long is too long?

AU - Koch, Colleen G.

AU - Figueroa, Priscilla I.

AU - Li, Liang

AU - Sabik, Joseph F.

AU - Mihaljevic, Tomislav

AU - Blackstone, Eugene H.

PY - 2013/11

Y1 - 2013/11

N2 - Red blood cells (RBCs) undergo biochemical and structural changes during storage, commonly referred to as the "storage lesion." Evidence suggests that the longer the RBC product is stored, the less effective is the transfused blood. Many studies linking morbidity to transfusion have not considered duration of RBC storage as a variable that may modulate the effect. In addition, the effects of supply and demand and RBC inventory management strategies have been incompletely investigated. It is possible to envision a blood management system based on modern inventory management strategies that could greatly reduce storage duration.

AB - Red blood cells (RBCs) undergo biochemical and structural changes during storage, commonly referred to as the "storage lesion." Evidence suggests that the longer the RBC product is stored, the less effective is the transfused blood. Many studies linking morbidity to transfusion have not considered duration of RBC storage as a variable that may modulate the effect. In addition, the effects of supply and demand and RBC inventory management strategies have been incompletely investigated. It is possible to envision a blood management system based on modern inventory management strategies that could greatly reduce storage duration.

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AN - SCOPUS:84887108554

SN - 0003-4975

VL - 96

SP - 1894

EP - 1899

JO - Annals of Thoracic Surgery

JF - Annals of Thoracic Surgery

IS - 5

ER -

Red blood cell storage: How long is too long?

Abstract

ASJC Scopus subject areas

MD Anderson CCSG core facilities

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