Reducing the effect of non-stationary resolution on activity quantitation with the frequency distance relationship in SPECT

P. H. Pretorius, M. A. King, S. J. Glick, T. S. Pan, D. S. Luo

Research output: Contribution to conferencePaperpeer-review

Abstract

The objective of this investigation is to determine if the FDR (Frequency Distance Relationship) restoration filtering can reduce the impact of distance dependent spatial resolution on the quantitation of activity. CCR's (Center Count Ratios) and TCR's (Total Count Ratios) are determined as the observed counts over true counts. Results show that after FDR restoration the CCR and TCR become approximately position invariant. However, when regularizing the FDR inverse filter with a Gaussian function, CCR's become highly unstable as the standard deviation (σ) decreased below that at the center of rotation. The use of the Gaussian and parametric Wiener filters to regularize FDR filtering introduce noise in the CCR's but improve recovery of TCR's over that of the center of rotation.

Original languageEnglish (US)
Pages1302-1306
Number of pages5
StatePublished - 1995
Externally publishedYes
EventProceedings of the 1995 IEEE Nuclear Science Symposium and Medical Imaging Conference. Part 1 (of 3) - San Francisco, CA, USA
Duration: Oct 21 1995Oct 28 1995

Other

OtherProceedings of the 1995 IEEE Nuclear Science Symposium and Medical Imaging Conference. Part 1 (of 3)
CitySan Francisco, CA, USA
Period10/21/9510/28/95

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging

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