静息心率与代谢综合征及10年心血管疾病的预测风险相关:一项横断面研究

Translated title of the contribution: Resting heart rate is associated with metabolic syndrome and predicted 10-year risk of cardiovascular disease: a cross-sectional study

Xueyan Wu, Rui Du, Chunyan Hu, Di Cheng, Lina Ma, Mian Li, Yu Xu, Min Xu, Yuhong Chen, Donghui Li, Yufang Bi, Weiqing Wang, Guang Ning, Jieli Lu

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: This study examined whether resting heart rate (RHR) was associated with metabolic syndrome (MetS) and the 10-year predicted risk of cardiovascular disease in a Chinese population. Methods: The associations of RHR with MetS and 10-year risk of atherosclerotic cardiovascular diseases (ASCVD) was examined in a cross-sectional study conducted in Shanghai, China (n = 9486). Results: Compared with individuals in the lowest RHR quintile (≤71 b.p.m.), those in the highest quintile (≥91 b.p.m.) had a higher prevalence of MetS (21.2% vs 32.6%, respectively; P < 0.001). Logistic regression analyses showed that the multivariate-adjusted odds ratio (OR) and 95% confidence interval (CI) for MetS was 1.13 (1.08-1.18) for each 10-b.p.m. increment of RHR (P < 0.0001). Furthermore, RHR was strongly associated with the prevalence of hypertension, high blood glucose, and dyslipidemia, but not with central obesity. A stronger association of RHR with MetS was observed among individuals aged <65 years, male, with a body mass index <24 kg/m2, without diabetes, hypertension, abnormal lipids, and insulin resistance than among their counterparts (P < 0.05 for all). A significantly higher 10-year risk for ASCVD was observed with each 10-b.p.m. increment in RHR in both men and women (ORs [95% CIs] 1.20 [1.07-1.33] and 1.28 [1.17-1.39], respectively; Ptrend = 0.002 and < 0.0001, respectively). Conclusions: In this study, RHR was associated with a higher prevalence of MetS and elevated 10-year predicted risk of ASCVD in both Chinese men and women. Whether RHR may serve as an indicator for MetS among relatively healthy individuals requires further investigation.

Original languageChinese
Pages (from-to)884-894
Number of pages11
JournalJournal of Diabetes
Volume11
Issue number11
DOIs
StatePublished - Nov 1 2019

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Cardiovascular Diseases
Cross-Sectional Studies
Heart Rate
Hypertension
Abdominal Obesity
Dyslipidemias
Insulin Resistance
Blood Glucose
China
Body Mass Index
Logistic Models
Odds Ratio
Regression Analysis
Confidence Intervals
Lipids
Population

Keywords

  • cardiovascular diseases
  • heart rate
  • metabolic syndrome

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism

Cite this

静息心率与代谢综合征及10年心血管疾病的预测风险相关:一项横断面研究. / Wu, Xueyan; Du, Rui; Hu, Chunyan; Cheng, Di; Ma, Lina; Li, Mian; Xu, Yu; Xu, Min; Chen, Yuhong; Li, Donghui; Bi, Yufang; Wang, Weiqing; Ning, Guang; Lu, Jieli.

In: Journal of Diabetes, Vol. 11, No. 11, 01.11.2019, p. 884-894.

Research output: Contribution to journalArticle

Wu, X, Du, R, Hu, C, Cheng, D, Ma, L, Li, M, Xu, Y, Xu, M, Chen, Y, Li, D, Bi, Y, Wang, W, Ning, G & Lu, J 2019, '静息心率与代谢综合征及10年心血管疾病的预测风险相关:一项横断面研究', Journal of Diabetes, vol. 11, no. 11, pp. 884-894. https://doi.org/10.1111/1753-0407.12927
Wu, Xueyan ; Du, Rui ; Hu, Chunyan ; Cheng, Di ; Ma, Lina ; Li, Mian ; Xu, Yu ; Xu, Min ; Chen, Yuhong ; Li, Donghui ; Bi, Yufang ; Wang, Weiqing ; Ning, Guang ; Lu, Jieli. / 静息心率与代谢综合征及10年心血管疾病的预测风险相关:一项横断面研究. In: Journal of Diabetes. 2019 ; Vol. 11, No. 11. pp. 884-894.
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abstract = "Background: This study examined whether resting heart rate (RHR) was associated with metabolic syndrome (MetS) and the 10-year predicted risk of cardiovascular disease in a Chinese population. Methods: The associations of RHR with MetS and 10-year risk of atherosclerotic cardiovascular diseases (ASCVD) was examined in a cross-sectional study conducted in Shanghai, China (n = 9486). Results: Compared with individuals in the lowest RHR quintile (≤71 b.p.m.), those in the highest quintile (≥91 b.p.m.) had a higher prevalence of MetS (21.2{\%} vs 32.6{\%}, respectively; P < 0.001). Logistic regression analyses showed that the multivariate-adjusted odds ratio (OR) and 95{\%} confidence interval (CI) for MetS was 1.13 (1.08-1.18) for each 10-b.p.m. increment of RHR (P < 0.0001). Furthermore, RHR was strongly associated with the prevalence of hypertension, high blood glucose, and dyslipidemia, but not with central obesity. A stronger association of RHR with MetS was observed among individuals aged <65 years, male, with a body mass index <24 kg/m2, without diabetes, hypertension, abnormal lipids, and insulin resistance than among their counterparts (P < 0.05 for all). A significantly higher 10-year risk for ASCVD was observed with each 10-b.p.m. increment in RHR in both men and women (ORs [95{\%} CIs] 1.20 [1.07-1.33] and 1.28 [1.17-1.39], respectively; Ptrend = 0.002 and < 0.0001, respectively). Conclusions: In this study, RHR was associated with a higher prevalence of MetS and elevated 10-year predicted risk of ASCVD in both Chinese men and women. Whether RHR may serve as an indicator for MetS among relatively healthy individuals requires further investigation.",
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AU - Wu, Xueyan

AU - Du, Rui

AU - Hu, Chunyan

AU - Cheng, Di

AU - Ma, Lina

AU - Li, Mian

AU - Xu, Yu

AU - Xu, Min

AU - Chen, Yuhong

AU - Li, Donghui

AU - Bi, Yufang

AU - Wang, Weiqing

AU - Ning, Guang

AU - Lu, Jieli

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N2 - Background: This study examined whether resting heart rate (RHR) was associated with metabolic syndrome (MetS) and the 10-year predicted risk of cardiovascular disease in a Chinese population. Methods: The associations of RHR with MetS and 10-year risk of atherosclerotic cardiovascular diseases (ASCVD) was examined in a cross-sectional study conducted in Shanghai, China (n = 9486). Results: Compared with individuals in the lowest RHR quintile (≤71 b.p.m.), those in the highest quintile (≥91 b.p.m.) had a higher prevalence of MetS (21.2% vs 32.6%, respectively; P < 0.001). Logistic regression analyses showed that the multivariate-adjusted odds ratio (OR) and 95% confidence interval (CI) for MetS was 1.13 (1.08-1.18) for each 10-b.p.m. increment of RHR (P < 0.0001). Furthermore, RHR was strongly associated with the prevalence of hypertension, high blood glucose, and dyslipidemia, but not with central obesity. A stronger association of RHR with MetS was observed among individuals aged <65 years, male, with a body mass index <24 kg/m2, without diabetes, hypertension, abnormal lipids, and insulin resistance than among their counterparts (P < 0.05 for all). A significantly higher 10-year risk for ASCVD was observed with each 10-b.p.m. increment in RHR in both men and women (ORs [95% CIs] 1.20 [1.07-1.33] and 1.28 [1.17-1.39], respectively; Ptrend = 0.002 and < 0.0001, respectively). Conclusions: In this study, RHR was associated with a higher prevalence of MetS and elevated 10-year predicted risk of ASCVD in both Chinese men and women. Whether RHR may serve as an indicator for MetS among relatively healthy individuals requires further investigation.

AB - Background: This study examined whether resting heart rate (RHR) was associated with metabolic syndrome (MetS) and the 10-year predicted risk of cardiovascular disease in a Chinese population. Methods: The associations of RHR with MetS and 10-year risk of atherosclerotic cardiovascular diseases (ASCVD) was examined in a cross-sectional study conducted in Shanghai, China (n = 9486). Results: Compared with individuals in the lowest RHR quintile (≤71 b.p.m.), those in the highest quintile (≥91 b.p.m.) had a higher prevalence of MetS (21.2% vs 32.6%, respectively; P < 0.001). Logistic regression analyses showed that the multivariate-adjusted odds ratio (OR) and 95% confidence interval (CI) for MetS was 1.13 (1.08-1.18) for each 10-b.p.m. increment of RHR (P < 0.0001). Furthermore, RHR was strongly associated with the prevalence of hypertension, high blood glucose, and dyslipidemia, but not with central obesity. A stronger association of RHR with MetS was observed among individuals aged <65 years, male, with a body mass index <24 kg/m2, without diabetes, hypertension, abnormal lipids, and insulin resistance than among their counterparts (P < 0.05 for all). A significantly higher 10-year risk for ASCVD was observed with each 10-b.p.m. increment in RHR in both men and women (ORs [95% CIs] 1.20 [1.07-1.33] and 1.28 [1.17-1.39], respectively; Ptrend = 0.002 and < 0.0001, respectively). Conclusions: In this study, RHR was associated with a higher prevalence of MetS and elevated 10-year predicted risk of ASCVD in both Chinese men and women. Whether RHR may serve as an indicator for MetS among relatively healthy individuals requires further investigation.

KW - cardiovascular diseases

KW - heart rate

KW - metabolic syndrome

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