Rethinking ovarian cancer II: Reducing mortality from high-grade serous ovarian cancer

David D. Bowtell; Steffen Böhm; Ahmed A. Ahmed; Paul Joseph Aspuria; Robert C. Bast; Valerie Beral; Jonathan S. Berek; Michael J. Birrer; Sarah Blagden; Michael A. Bookman; James D. Brenton; Katherine B. Chiappinelli; Filipe Correia Martins; George Coukos; Ronny Drapkin; Richard Edmondson; Christina Fotopoulou; Hani Gabra; Jérôme Galon; Charlie Gourley; Valerie Heong; David G. Huntsman; Marcin Iwanicki; Beth Y. Karlan; Allyson Kaye; Ernst Lengyel; Douglas A. Levine; Karen H. Lu; Iain A. McNeish; Usha Menon; Steven A. Narod; Brad H. Nelson; Kenneth P. Nephew; Paul Pharoah; Daniel J. Powell; Pilar Ramos; Iris L. Romero; Clare L. Scott; Anil K. Sood; Euan A. Stronach; Frances R. Balkwill

doi:10.1038/nrc4019

Rethinking ovarian cancer II: Reducing mortality from high-grade serous ovarian cancer

David D. Bowtell, Steffen Böhm, Ahmed A. Ahmed, Paul Joseph Aspuria, Robert C. Bast, Valerie Beral, Jonathan S. Berek, Michael J. Birrer, Sarah Blagden, Michael A. Bookman, James D. Brenton, Katherine B. Chiappinelli, Filipe Correia Martins, George Coukos, Ronny Drapkin, Richard Edmondson, Christina Fotopoulou, Hani Gabra, Jérôme Galon, Charlie GourleyValerie Heong, David G. Huntsman, Marcin Iwanicki, Beth Y. Karlan, Allyson Kaye, Ernst Lengyel, Douglas A. Levine, Karen H. Lu, Iain A. McNeish, Usha Menon, Steven A. Narod, Brad H. Nelson, Kenneth P. Nephew, Paul Pharoah, Daniel J. Powell, Pilar Ramos, Iris L. Romero, Clare L. Scott, Anil K. Sood, Euan A. Stronach, Frances R. Balkwill

Research output: Contribution to journal › Review article › peer-review

767 Scopus citations

Abstract

High-grade serous ovarian cancer (HGSOC) accounts for 70-80% of ovarian cancer deaths, and overall survival has not changed significantly for several decades. In this Opinion article, we outline a set of research priorities that we believe will reduce incidence and improve outcomes for women with this disease. This 'roadmap' for HGSOC was determined after extensive discussions at an Ovarian Cancer Action meeting in January 2015.

Original language	English (US)
Pages (from-to)	668-679
Number of pages	12
Journal	Nature Reviews Cancer
Volume	15
Issue number	11
DOIs	https://doi.org/10.1038/nrc4019
State	Published - Oct 23 2015

ASJC Scopus subject areas

Oncology
Cancer Research

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Bowtell, D. D., Böhm, S., Ahmed, A. A., Aspuria, P. J., Bast, R. C., Beral, V., Berek, J. S., Birrer, M. J., Blagden, S., Bookman, M. A., Brenton, J. D., Chiappinelli, K. B., Martins, F. C., Coukos, G., Drapkin, R., Edmondson, R., Fotopoulou, C., Gabra, H., Galon, J., ... Balkwill, F. R. (2015). Rethinking ovarian cancer II: Reducing mortality from high-grade serous ovarian cancer. Nature Reviews Cancer, 15(11), 668-679. https://doi.org/10.1038/nrc4019

Bowtell, DD, Böhm, S, Ahmed, AA, Aspuria, PJ, Bast, RC, Beral, V, Berek, JS, Birrer, MJ, Blagden, S, Bookman, MA, Brenton, JD, Chiappinelli, KB, Martins, FC, Coukos, G, Drapkin, R, Edmondson, R, Fotopoulou, C, Gabra, H, Galon, J, Gourley, C, Heong, V, Huntsman, DG, Iwanicki, M, Karlan, BY, Kaye, A, Lengyel, E, Levine, DA, Lu, KH, McNeish, IA, Menon, U, Narod, SA, Nelson, BH, Nephew, KP, Pharoah, P, Powell, DJ, Ramos, P, Romero, IL, Scott, CL, Sood, AK, Stronach, EA & Balkwill, FR 2015, 'Rethinking ovarian cancer II: Reducing mortality from high-grade serous ovarian cancer', Nature Reviews Cancer, vol. 15, no. 11, pp. 668-679. https://doi.org/10.1038/nrc4019

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title = "Rethinking ovarian cancer II: Reducing mortality from high-grade serous ovarian cancer",

abstract = "High-grade serous ovarian cancer (HGSOC) accounts for 70-80% of ovarian cancer deaths, and overall survival has not changed significantly for several decades. In this Opinion article, we outline a set of research priorities that we believe will reduce incidence and improve outcomes for women with this disease. This 'roadmap' for HGSOC was determined after extensive discussions at an Ovarian Cancer Action meeting in January 2015.",

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AU - Edmondson, Richard

AU - Fotopoulou, Christina

AU - Gabra, Hani

AU - Galon, Jérôme

AU - Gourley, Charlie

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AU - Levine, Douglas A.

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AU - Narod, Steven A.

AU - Nelson, Brad H.

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AU - Powell, Daniel J.

AU - Ramos, Pilar

AU - Romero, Iris L.

AU - Scott, Clare L.

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Rethinking ovarian cancer II: Reducing mortality from high-grade serous ovarian cancer

Abstract

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