Abstract
Based on a variety of preclinical studies showing that mesenchymal stem cells (MSC) play a significant role in tissue repair and homeostasis, MSC have rapidly moved into a phase of clinical trials investigating their efficacy as a cell-based therapeutic modality for a diverse group of applications. An emerging body of evidence shows that in addition to being a progenitor cell population with self-renewing and multipotent differentiation capabilities, MSC have unique immunomodulatory properties, making them even more attractive for regenerative medicine. Emerging discoveries in stem cell biology have revealed a multitude of mechanisms through which MSC could potentially augment the current techniques in aesthetic surgery. In this article, the authors review the clinical advances in cell-based therapies relevant to aesthetic surgery, including tissue augmentation, rejuvenation, and regeneration.
Original language | English (US) |
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Pages (from-to) | 838-842 |
Number of pages | 5 |
Journal | Aesthetic surgery journal |
Volume | 30 |
Issue number | 6 |
DOIs | |
State | Published - Dec 2010 |
Keywords
- cosmetic augmentation
- fat grafting
- immune modulation
- mesenchymal stem cells
ASJC Scopus subject areas
- Surgery