Risikoen for kolorektal cancer og andre cancersygdomme hos patienter med galdesten

Translated title of the contribution: Risk of colorectal cancer and other navigranis in patients with gallstones

Christoffer Johansen, Wong-Ho Chow, Torben Jørgensen, Lene Mellemkjœr, Jørgen H. Olsen

Research output: Contribution to journalArticle

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Abstract

In a nationwide cohort of gallstone patients we evaluated the hypothesis that gall stones are associated with an increased risk of cancer of the colon. In the Danish Hospital Discharge Register we identified 42,098 patients with gallstones diagnosed in 1977-1989. These patients were linked to the Danish Cancer Registry in order to assess their risks of colorectal and other cancers during follow-up to the end of 1992. The analysis showed a modest increase in the number of cancers at all sites combined (N=3940; RR=1.07; 95% CI=1.0-1.1). Aweak association was found for cancer of the colon (N=360; RR=1.09; 95% CI=1.0-1.2), which remained unchanged when analysed by sex, anatomical subsite and duration of follow-up. Multivariate analysis with adjustment for cholecystectomy and clinically defined obesity did not change these estimates to any significant extent. A non-significantly increased risk of breast cancer was seen in women five years after initial discharge for gallstones.

Original languageDanish
Pages (from-to)831-835
Number of pages5
JournalUgeskrift for laeger
Volume160
Issue number6
StatePublished - Feb 2 1998

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Johansen, C., Chow, W-H., Jørgensen, T., Mellemkjœr, L., & Olsen, J. H. (1998). Risikoen for kolorektal cancer og andre cancersygdomme hos patienter med galdesten. Ugeskrift for laeger, 160(6), 831-835.