Selective oestrogen receptor modulationmolecular pharmacology for the millennium

A. S. Levenson; V. C. Jordan

doi:10.1016/S0959-8049(99)00297-X

Selective oestrogen receptor modulationmolecular pharmacology for the millennium

A. S. Levenson
, V. C. Jordan

Research output: Contribution to journal › Article › peer-review

60 Scopus citations

Abstract

Knowledge of the mechanism of action and pharmacology of tamoxifen and raloxifene, for the prevention of breast cancer and osteoporosis respectively, has opened the door for the discovery of multifunctional medicines. There is now the potential to prevent osteoporosis, coronary heart disease, breast and endometrial cancer in postmenopausal women with elevated risk factors. Copyright (C) 1999 Elsevier Science Ltd.

Original language	English (US)
Pages (from-to)	1974-1985
Number of pages	12
Journal	European Journal of Cancer
Volume	35
Issue number	14
DOIs	https://doi.org/10.1016/S0959-8049(99)00297-X
State	Published - Dec 1999
Externally published	Yes

Keywords

Breast cancer
Prevention
Raloxifene
Tamoxifen

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1016/S0959-8049(99)00297-X

Cite this

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title = "Selective oestrogen receptor modulationmolecular pharmacology for the millennium",

abstract = "Knowledge of the mechanism of action and pharmacology of tamoxifen and raloxifene, for the prevention of breast cancer and osteoporosis respectively, has opened the door for the discovery of multifunctional medicines. There is now the potential to prevent osteoporosis, coronary heart disease, breast and endometrial cancer in postmenopausal women with elevated risk factors. Copyright (C) 1999 Elsevier Science Ltd.",

keywords = "Breast cancer, Prevention, Raloxifene, Tamoxifen",

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AU - Jordan, V. C.

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N2 - Knowledge of the mechanism of action and pharmacology of tamoxifen and raloxifene, for the prevention of breast cancer and osteoporosis respectively, has opened the door for the discovery of multifunctional medicines. There is now the potential to prevent osteoporosis, coronary heart disease, breast and endometrial cancer in postmenopausal women with elevated risk factors. Copyright (C) 1999 Elsevier Science Ltd.

AB - Knowledge of the mechanism of action and pharmacology of tamoxifen and raloxifene, for the prevention of breast cancer and osteoporosis respectively, has opened the door for the discovery of multifunctional medicines. There is now the potential to prevent osteoporosis, coronary heart disease, breast and endometrial cancer in postmenopausal women with elevated risk factors. Copyright (C) 1999 Elsevier Science Ltd.

KW - Breast cancer

KW - Prevention

KW - Raloxifene

KW - Tamoxifen

UR - https://www.scopus.com/pages/publications/0033372865

UR - https://www.scopus.com/pages/publications/0033372865#tab=citedBy

U2 - 10.1016/S0959-8049(99)00297-X

DO - 10.1016/S0959-8049(99)00297-X

M3 - Article

C2 - 10711240

AN - SCOPUS:0033372865

SN - 0959-8049

VL - 35

SP - 1974

EP - 1985

JO - European Journal of Cancer

JF - European Journal of Cancer

IS - 14

ER -

Selective oestrogen receptor modulationmolecular pharmacology for the millennium

Abstract

Keywords

ASJC Scopus subject areas

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