Abstract
In the 1990s, the technique of sentinel lymph node (SLN) biopsy was developed as a less morbid alternative to complete lymphadenectomy [1–3]. SLN biopsy is based on the principle that the disease status of the first node in the lymphatic chain to which the tumor drains is representative of the disease status of the rest of the nodes in the chain. If pathologic analysis demonstrates that the SLN is cancer-free, then there is no need for complete lymphadenectomy. As many malignancies in the periocular region have the potential to metastasize to the regional lymph nodes, sentinel lymph node biopsy has been evaluated for early identification of microscopic lymph node metastasis in patients with cancers of the eyelid and conjunctiva. This chapter summarizes the anatomic considerations, technical modifications, and indications for SLN biopsy in the periocular region and will review the published reports to date on this topic.
Original language | English (US) |
---|---|
Title of host publication | Clinical Ophthalmic Oncology |
Subtitle of host publication | Eyelid and Conjunctival Tumors |
Publisher | Springer Berlin Heidelberg |
Pages | 111-124 |
Number of pages | 14 |
ISBN (Electronic) | 9783642383366 |
ISBN (Print) | 9783642383359 |
DOIs | |
State | Published - Jan 1 2014 |
ASJC Scopus subject areas
- General Medicine