Sentinel lymph node assessment and biopsy for eyelid and conjunctival malignancies

Vivian T. Yin, Bita Esmaeli

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

In the 1990s, the technique of sentinel lymph node (SLN) biopsy was developed as a less morbid alternative to complete lymphadenectomy [1–3]. SLN biopsy is based on the principle that the disease status of the first node in the lymphatic chain to which the tumor drains is representative of the disease status of the rest of the nodes in the chain. If pathologic analysis demonstrates that the SLN is cancer-free, then there is no need for complete lymphadenectomy. As many malignancies in the periocular region have the potential to metastasize to the regional lymph nodes, sentinel lymph node biopsy has been evaluated for early identification of microscopic lymph node metastasis in patients with cancers of the eyelid and conjunctiva. This chapter summarizes the anatomic considerations, technical modifications, and indications for SLN biopsy in the periocular region and will review the published reports to date on this topic.

Original languageEnglish (US)
Title of host publicationClinical Ophthalmic Oncology
Subtitle of host publicationEyelid and Conjunctival Tumors
PublisherSpringer Berlin Heidelberg
Pages111-124
Number of pages14
ISBN (Electronic)9783642383366
ISBN (Print)9783642383359
DOIs
StatePublished - Jan 1 2014

ASJC Scopus subject areas

  • General Medicine

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