Simple, high yielding synthesis of trifunctional fluorescent lanthanide chelates

John M.M. Griffin; Anna M. Skwierawska; H. Charles Manning; John N. Marx; Darryl J. Bornhop

doi:10.1016/S0040-4039(01)00620-7

Simple, high yielding synthesis of trifunctional fluorescent lanthanide chelates

John M.M. Griffin
, Anna M. Skwierawska
, H. Charles Manning
, John N. Marx
, Darryl J. Bornhop

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

In an effort to produce strong fluorophores which are conjugated to biologically active substrates, we report a facile, high yielding synthesis of conjugable lanthanide chelates based on the cyclen (1,4,7,10-tetraazacyclododecane) macrocycle.

Original language	English (US)
Pages (from-to)	3823-3825
Number of pages	3
Journal	Tetrahedron Letters
Volume	42
Issue number	23
DOIs	https://doi.org/10.1016/S0040-4039(01)00620-7
State	Published - Jun 4 2001
Externally published	Yes

Keywords

1,4,7,10-tetraazacyclododecane
Chelate
Conjugates
Fluorescence
Lanthanide

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(01)00620-7

Cite this

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title = "Simple, high yielding synthesis of trifunctional fluorescent lanthanide chelates",

abstract = "In an effort to produce strong fluorophores which are conjugated to biologically active substrates, we report a facile, high yielding synthesis of conjugable lanthanide chelates based on the cyclen (1,4,7,10-tetraazacyclododecane) macrocycle.",

keywords = "1,4,7,10-tetraazacyclododecane, Chelate, Conjugates, Fluorescence, Lanthanide",

author = "Griffin, \{John M.M.\} and Skwierawska, \{Anna M.\} and Manning, \{H. Charles\} and Marx, \{John N.\} and Bornhop, \{Darryl J.\}",

note = "Funding Information: This work was supported by grants from the Whitaker Foundation and The Southwest Cancer Center.",

year = "2001",

month = jun,

day = "4",

doi = "10.1016/S0040-4039(01)00620-7",

language = "English (US)",

volume = "42",

pages = "3823--3825",

journal = "Tetrahedron Letters",

issn = "0040-4039",

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TY - JOUR

T1 - Simple, high yielding synthesis of trifunctional fluorescent lanthanide chelates

AU - Griffin, John M.M.

AU - Skwierawska, Anna M.

AU - Manning, H. Charles

AU - Marx, John N.

AU - Bornhop, Darryl J.

N1 - Funding Information: This work was supported by grants from the Whitaker Foundation and The Southwest Cancer Center.

PY - 2001/6/4

Y1 - 2001/6/4

N2 - In an effort to produce strong fluorophores which are conjugated to biologically active substrates, we report a facile, high yielding synthesis of conjugable lanthanide chelates based on the cyclen (1,4,7,10-tetraazacyclododecane) macrocycle.

AB - In an effort to produce strong fluorophores which are conjugated to biologically active substrates, we report a facile, high yielding synthesis of conjugable lanthanide chelates based on the cyclen (1,4,7,10-tetraazacyclododecane) macrocycle.

KW - 1,4,7,10-tetraazacyclododecane

KW - Chelate

KW - Conjugates

KW - Fluorescence

KW - Lanthanide

UR - https://www.scopus.com/pages/publications/0035806266

UR - https://www.scopus.com/pages/publications/0035806266#tab=citedBy

U2 - 10.1016/S0040-4039(01)00620-7

DO - 10.1016/S0040-4039(01)00620-7

M3 - Article

AN - SCOPUS:0035806266

SN - 0040-4039

VL - 42

SP - 3823

EP - 3825

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 23

ER -

Simple, high yielding synthesis of trifunctional fluorescent lanthanide chelates

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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