TY - JOUR
T1 - Spectrum of Xanthogranulomatous processes in the abdomen and pelvis
T2 - A pictorial review of infectious, inflammatory, and proliferative responses
AU - Bourm, Kelsey S.
AU - Menias, Christine O.
AU - Ali, Kamran
AU - Alhalabi, Kinan
AU - Elsayes, Khaled M.
N1 - Publisher Copyright:
© 2017 American Roentgen Ray Society.
PY - 2017/3
Y1 - 2017/3
N2 - OBJECTIVE. Xanthogranulomatous (XG) processes are rare inflammatory conditions with the characteristic pathologic feature of lipid-laden macrophages or histiocyte cells. Imaging findings are nonspecific and can simulate aggressive neoplastic processes. XG processes can be caused by infection, inflammation, histolytic process, or an inherited lysosomal disorder. XG infectious processes are mainly seen in cholecystitis and pyelonephritis, but several other organs can also be involved. Histiocytic processes can be divided into Langerhans and non-Langerhans cell histiocytosis. The non-Langerhans cell histiocytosis entities include Erdheim-Chester disease, Rosai-Dorfman disease, juvenile xanthogranuloma, and hemophagocytic lymphohistiocytosis. The inherited lysosomal disorders resulting in XG processes include Nieman-Pick, Gaucher, and other lysosomal storage disorders. CONCLUSION. Radiologists need to be able to recognize features of xanthogranulomatous processes to help facilitate patient management.
AB - OBJECTIVE. Xanthogranulomatous (XG) processes are rare inflammatory conditions with the characteristic pathologic feature of lipid-laden macrophages or histiocyte cells. Imaging findings are nonspecific and can simulate aggressive neoplastic processes. XG processes can be caused by infection, inflammation, histolytic process, or an inherited lysosomal disorder. XG infectious processes are mainly seen in cholecystitis and pyelonephritis, but several other organs can also be involved. Histiocytic processes can be divided into Langerhans and non-Langerhans cell histiocytosis. The non-Langerhans cell histiocytosis entities include Erdheim-Chester disease, Rosai-Dorfman disease, juvenile xanthogranuloma, and hemophagocytic lymphohistiocytosis. The inherited lysosomal disorders resulting in XG processes include Nieman-Pick, Gaucher, and other lysosomal storage disorders. CONCLUSION. Radiologists need to be able to recognize features of xanthogranulomatous processes to help facilitate patient management.
KW - Cholecystitis
KW - Erdheim-Chester disease
KW - Hemophagocytic lymphohistiocytosis
KW - Infection
KW - Inflammation
KW - Juvenile xanthogranuloma
KW - Pyelonephritis
KW - Rosai-Dorfman disease
KW - Xanthogranulomatous process
UR - http://www.scopus.com/inward/record.url?scp=85013668940&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85013668940&partnerID=8YFLogxK
U2 - 10.2214/AJR.16.17075
DO - 10.2214/AJR.16.17075
M3 - Review article
C2 - 28095017
AN - SCOPUS:85013668940
SN - 0361-803X
VL - 208
SP - 475
EP - 484
JO - American Journal of Roentgenology
JF - American Journal of Roentgenology
IS - 3
ER -