Abstract
The methylation of mammalian DNA, primarily at CpG dinucleotides, has long been recognized to play a major role in controlling gene expression among other functions. Given their importance, it is surprising how many basic questions remain to be answered about the proteins responsible for this methylation and for coordination with the parallel chromatin-marking system that operates at the level of histone modification.
| Original language | English (US) |
|---|---|
| Title of host publication | DNA and RNA Modification Enzymes |
| Subtitle of host publication | Structure, Mechanism, Function and Evolution |
| Publisher | CRC Press |
| Pages | 87-102 |
| Number of pages | 16 |
| ISBN (Electronic) | 9781498713153 |
| ISBN (Print) | 9781587063299 |
| State | Published - Jan 1 2009 |
| Externally published | Yes |
ASJC Scopus subject areas
- General Agricultural and Biological Sciences
- General Biochemistry, Genetics and Molecular Biology