18 Fluorodeoxyglucose-positron emission tomography/computed tomography features of suspected solitary pulmonary lesions in breast cancer patients following previous curative treatment

Lei Zhu, Haiman Bian, Lieming Yang, Jianjing Liu, Wei Chen, Xiaofeng Li, Jian Wang, Xiuyu Song, Dong Dai, Zhaoxiang Ye, Wengui Xu, Xiaozhou Yu

Research output: Contribution to journalArticle

Abstract

Background: Differentiating pulmonary metastasis from primary lung cancer can be challenging in patients with breast malignancy. This study aimed to characterize the imaging features of 18 fluorodeoxyglucose-positron emission tomography/computed tomography ( 18 F-FDG-PET/CT) for distinguishing between these diseases. Methods: We enrolled 52 patients who received curative treatment for breast cancer but later presented with suspected solitary pulmonary lesions (SPLs) and subsequently underwent 18 F-FDG-PET/CT to investigate. Results: Subsolid lesions, ill-defined borders, lung lesions with negative maximum standardized uptake value, and lesions without 18 F-FDG-PET/CT-diagnosed hilar and/or mediastinal lymph nodes and pleural metastases were more likely to be associated with primary lung cancer. Conclusions: CT border, FDG uptake, hilar and/or mediastinal lymph node metastasis, and pleural metastasis are potential markers for diagnosis.

Original languageEnglish (US)
Pages (from-to)1086-1095
Number of pages10
JournalThoracic Cancer
Volume10
Issue number5
DOIs
StatePublished - May 1 2019

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Breast Neoplasms
Neoplasm Metastasis
Lung
Lung Neoplasms
Lymph Nodes
Therapeutics
Breast
Positron Emission Tomography Computed Tomography
Neoplasms

Keywords

  • Fluorodeoxyglucose-positron emission tomography/computed tomography
  • breast cancer metastasis
  • lung cancer
  • solitary pulmonary lesion

ASJC Scopus subject areas

  • Oncology
  • Pulmonary and Respiratory Medicine

Cite this

18 Fluorodeoxyglucose-positron emission tomography/computed tomography features of suspected solitary pulmonary lesions in breast cancer patients following previous curative treatment . / Zhu, Lei; Bian, Haiman; Yang, Lieming; Liu, Jianjing; Chen, Wei; Li, Xiaofeng; Wang, Jian; Song, Xiuyu; Dai, Dong; Ye, Zhaoxiang; Xu, Wengui; Yu, Xiaozhou.

In: Thoracic Cancer, Vol. 10, No. 5, 01.05.2019, p. 1086-1095.

Research output: Contribution to journalArticle

Zhu, Lei ; Bian, Haiman ; Yang, Lieming ; Liu, Jianjing ; Chen, Wei ; Li, Xiaofeng ; Wang, Jian ; Song, Xiuyu ; Dai, Dong ; Ye, Zhaoxiang ; Xu, Wengui ; Yu, Xiaozhou. / 18 Fluorodeoxyglucose-positron emission tomography/computed tomography features of suspected solitary pulmonary lesions in breast cancer patients following previous curative treatment In: Thoracic Cancer. 2019 ; Vol. 10, No. 5. pp. 1086-1095.
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abstract = "Background: Differentiating pulmonary metastasis from primary lung cancer can be challenging in patients with breast malignancy. This study aimed to characterize the imaging features of 18 fluorodeoxyglucose-positron emission tomography/computed tomography ( 18 F-FDG-PET/CT) for distinguishing between these diseases. Methods: We enrolled 52 patients who received curative treatment for breast cancer but later presented with suspected solitary pulmonary lesions (SPLs) and subsequently underwent 18 F-FDG-PET/CT to investigate. Results: Subsolid lesions, ill-defined borders, lung lesions with negative maximum standardized uptake value, and lesions without 18 F-FDG-PET/CT-diagnosed hilar and/or mediastinal lymph nodes and pleural metastases were more likely to be associated with primary lung cancer. Conclusions: CT border, FDG uptake, hilar and/or mediastinal lymph node metastasis, and pleural metastasis are potential markers for diagnosis.",
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AU - Zhu, Lei

AU - Bian, Haiman

AU - Yang, Lieming

AU - Liu, Jianjing

AU - Chen, Wei

AU - Li, Xiaofeng

AU - Wang, Jian

AU - Song, Xiuyu

AU - Dai, Dong

AU - Ye, Zhaoxiang

AU - Xu, Wengui

AU - Yu, Xiaozhou

PY - 2019/5/1

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N2 - Background: Differentiating pulmonary metastasis from primary lung cancer can be challenging in patients with breast malignancy. This study aimed to characterize the imaging features of 18 fluorodeoxyglucose-positron emission tomography/computed tomography ( 18 F-FDG-PET/CT) for distinguishing between these diseases. Methods: We enrolled 52 patients who received curative treatment for breast cancer but later presented with suspected solitary pulmonary lesions (SPLs) and subsequently underwent 18 F-FDG-PET/CT to investigate. Results: Subsolid lesions, ill-defined borders, lung lesions with negative maximum standardized uptake value, and lesions without 18 F-FDG-PET/CT-diagnosed hilar and/or mediastinal lymph nodes and pleural metastases were more likely to be associated with primary lung cancer. Conclusions: CT border, FDG uptake, hilar and/or mediastinal lymph node metastasis, and pleural metastasis are potential markers for diagnosis.

AB - Background: Differentiating pulmonary metastasis from primary lung cancer can be challenging in patients with breast malignancy. This study aimed to characterize the imaging features of 18 fluorodeoxyglucose-positron emission tomography/computed tomography ( 18 F-FDG-PET/CT) for distinguishing between these diseases. Methods: We enrolled 52 patients who received curative treatment for breast cancer but later presented with suspected solitary pulmonary lesions (SPLs) and subsequently underwent 18 F-FDG-PET/CT to investigate. Results: Subsolid lesions, ill-defined borders, lung lesions with negative maximum standardized uptake value, and lesions without 18 F-FDG-PET/CT-diagnosed hilar and/or mediastinal lymph nodes and pleural metastases were more likely to be associated with primary lung cancer. Conclusions: CT border, FDG uptake, hilar and/or mediastinal lymph node metastasis, and pleural metastasis are potential markers for diagnosis.

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