18F-Fluciclovine-Avid Reactive Axillary Lymph Nodes After COVID-19 Vaccination

Franklin C. Wong, Lucia Martiniova, Avantika Masrani, Gregory C. Ravizzini

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


A 74-year-old man presenting with biochemical recurrent prostate cancer 9 months after robotic-assisted radical prostatectomy and pelvic lymphadenectomy underwent 18F-fluciclovine PET/CT for restaging to determine subsequent treatment strategy. Serum prostate-specific antigen was 0.7 ng/mL at the time of imaging. Images demonstrated foci of abnormal increased 18F-fluciclovine uptake corresponding to prominent round lymph nodes in the left axilla, some of which with fatty hila. Due to recent mRNA COVID-19 vaccination in the ipsilateral arm and the low likelihood of nodal metastases to the axilla from prostate cancer in this patient, the lymph nodes were considered to be benign, reactive to the vaccine.

Original languageEnglish (US)
Pages (from-to)154-155
Number of pages2
JournalClinical nuclear medicine
Issue number2
StatePublished - Feb 1 2022


  • F-fluciclovine
  • COVID-19
  • false-positive
  • lymphadenopathy
  • PET/CT
  • SARS-CoV-2

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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