TY - JOUR
T1 - Surgical clinical trials in melanoma
AU - Bedrosian, Isabelle
AU - Gershenwald, Jeffrey E.
PY - 2003/4/1
Y1 - 2003/4/1
N2 - Over the past 30 years, several important surgery clinical trials examining the issues of excision margins, ELND, and regional therapy have given rise to the current practice guidelines for the care of melanoma patients. The development of the SLN selective lymphadenectomy concept and the increasing use of molecular staging techniques have presented new challenges in this field. Clinical trials have been initiated to address these latest issues. In the next decade, these trials should help guide the integration of the new technologies into the surgical management of melanoma.
AB - Over the past 30 years, several important surgery clinical trials examining the issues of excision margins, ELND, and regional therapy have given rise to the current practice guidelines for the care of melanoma patients. The development of the SLN selective lymphadenectomy concept and the increasing use of molecular staging techniques have presented new challenges in this field. Clinical trials have been initiated to address these latest issues. In the next decade, these trials should help guide the integration of the new technologies into the surgical management of melanoma.
UR - http://www.scopus.com/inward/record.url?scp=0037397133&partnerID=8YFLogxK
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U2 - 10.1016/S0039-6109(02)00099-3
DO - 10.1016/S0039-6109(02)00099-3
M3 - Review article
C2 - 12744615
AN - SCOPUS:0037397133
SN - 0039-6109
VL - 83
SP - 385
EP - 403
JO - Surgical Clinics of North America
JF - Surgical Clinics of North America
IS - 2
ER -