TY - JOUR
T1 - Surgical Resection
T2 - Old Dog, Any New Tricks?
AU - Kawaguchi, Yoshikuni
AU - Lillemoe, Heather A.
AU - Vauthey, Jean Nicolas
N1 - Publisher Copyright:
© 2020 Elsevier Inc.
PY - 2020/11
Y1 - 2020/11
N2 - Patients with hepatocellular carcinoma (HCC) have many treatment options. For patients with surgical indication, consideration of future liver remnant and the surgical complexity of the procedure is essential. A new 3-level complexity classification categorizing 11 liver resection procedures predicts surgical complexity and postoperative morbidity better than reported classifications. Preoperative portal vein embolization can mitigate the risk of hepatic insufficiency. For small HCCs, both liver resection and ablation are effective. New medical treatment options are promising and perioperative use of these drugs may further improve outcomes for patients undergoing liver resection and lead to changes in current treatment guidelines.
AB - Patients with hepatocellular carcinoma (HCC) have many treatment options. For patients with surgical indication, consideration of future liver remnant and the surgical complexity of the procedure is essential. A new 3-level complexity classification categorizing 11 liver resection procedures predicts surgical complexity and postoperative morbidity better than reported classifications. Preoperative portal vein embolization can mitigate the risk of hepatic insufficiency. For small HCCs, both liver resection and ablation are effective. New medical treatment options are promising and perioperative use of these drugs may further improve outcomes for patients undergoing liver resection and lead to changes in current treatment guidelines.
KW - Future liver remnant
KW - Hepatocellular carcinoma
KW - Immunotherapy
KW - Laparoscopic liver resection
KW - Liver resection
KW - Major resection
KW - Portal vein embolization
KW - Surgery
UR - http://www.scopus.com/inward/record.url?scp=85090059840&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85090059840&partnerID=8YFLogxK
U2 - 10.1016/j.cld.2020.07.004
DO - 10.1016/j.cld.2020.07.004
M3 - Review article
C2 - 33012450
AN - SCOPUS:85090059840
SN - 1089-3261
VL - 24
SP - 637
EP - 655
JO - Clinics in Liver Disease
JF - Clinics in Liver Disease
IS - 4
ER -