Synthesis of a 2(1 h)-pyridone library via rhodium-catalyzed formation of isomunchones

Subhasis De, Lu Chen, Shuxing Zhang, Scott R. Gilbertson

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Through the use of the dipolar cycloaddition of isomunchones with olefins the 2(1H)-pyridone ring system has been synthesized.(1) The use of different cyclization partners followed by diversification of the initial scaffold has provded libraries of 4-hydroxy-2(1H)-pyridones. There are no examples of this ring system in either PubChem or the MLSMR

Original languageEnglish (US)
Pages (from-to)340-343
Number of pages4
JournalACS Combinatorial Science
Volume15
Issue number7
DOIs
StatePublished - Jul 8 2013

Keywords

  • carbene
  • isomunchone
  • pyridone
  • rhodium

ASJC Scopus subject areas

  • General Chemistry

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