Telomeres: history, health, and hallmarks of aging

Deepavali Chakravarti, Kyle A. LaBella, Ronald A. DePinho

Research output: Contribution to journalReview articlepeer-review

209 Scopus citations

Abstract

Telomere attrition and dysfunction causes and consequences of cellular and molecular aging and age-related disease. Mounting data revel how telomeres are entwined with other aging hallmarks and may be therapeutic targets for aging and age-related disease.

Original languageEnglish (US)
Pages (from-to)306-322
Number of pages17
JournalCell
Volume184
Issue number2
DOIs
StatePublished - Jan 21 2021

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology

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