Abstract
Recent developments in the field of molecular biology including the sequencing of the human genome and related high throughput methodologies are presenting the diagnostic pathologist with new opportunities to expand our understanding of human disease. These techniques enable the comprehensive assessment of molecular alterations with cell populations of interest, including cancer. It will be necessary for the diagnostic pathologist to become familiar with these techniques to effectively translate their potential into the clinical environment.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 94-103 |
| Number of pages | 10 |
| Journal | Seminars in Diagnostic Pathology |
| Volume | 19 |
| Issue number | 2 |
| State | Published - 2002 |
Keywords
- Comparative genomic hybridization
- Fluorescent in situ hybridization
- Laser capture microscopy
- Proteomics
- Reverse transcription polymerase reaction
- Serial analysis of gene expression
- Single nucleotide polymorphisms
- Tissue microarrays
- cDNA arrays
ASJC Scopus subject areas
- Pathology and Forensic Medicine
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