The cancer genome

Michael R. Stratton, Peter J. Campbell, P. Andrew Futreal

Research output: Contribution to journalReview articlepeer-review

1965 Scopus citations

Abstract

All cancers arise as a result of changes that have occurred in the DNA sequence of the genomes of cancer cells. Over the past quarter of a century much has been learnt about these mutations and the abnormal genes that operate in human cancers. We are now, however, moving into an era in which it will be possible to obtain the complete DNA sequence of large numbers of cancer genomes. These studies will provide us with a detailed and comprehensive perspective on how individual cancers have developed.

Original languageEnglish (US)
Pages (from-to)719-724
Number of pages6
JournalNature
Volume458
Issue number7239
DOIs
StatePublished - Apr 9 2009

ASJC Scopus subject areas

  • General

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