@inbook{30cced8ef74c45a29de980db838344e5,
title = "The HPA-axis and immune function in burnout",
abstract = "Burnout results from chronic work stress. Its complaints may be related to HPA-axis disturbances or changes in immune function. In our studies the salivary cortisol awakening response, day-curve, and the suppressed level after dexamethasone intake were not different in a burned-out group compared to a control group. Nor was there a change in cortisol after a treatment period. Higher levels of DHEAS and the monocyte released anti-inflammatory cytokine IL-10 were observed, however T-cell stimulated and dexamethasone inhibited cytokine release were not affected. The increased IL-10 level may be related to an increased sensitivity for infections.",
keywords = "DHEAS, burnout, chronic stress, cortisol, cytokines, dexamethasone suppression test, follow-up",
author = "Mommersteeg, {Paula M.C.} and Heijnen, {Cobi J.} and Annemieke Kavelaars and {van Doornen}, {Lorenz J.P.}",
note = "Funding Information: This research was granted by the Netherlands Organisation for scientific Research (NWO) as part of the Netherlands research program {\textquoteleft}fatigue at work{\textquoteright} (NWO grant 580-02.108).",
year = "2007",
doi = "10.1016/S0079-6123(07)67024-1",
language = "English (US)",
isbn = "0444531408",
series = "Progress in Brain Research",
pages = "281--285",
editor = "Ronlad Kloet and Melly Oitzl and Eric Vermetten",
booktitle = "Stress Hormones and Post Traumatic Stress Disorder Basic Studies and Clinical Perspectives",
}