The impact of gene mapping techniques on the management of multiple endocrine neoplasia type 2

Research output: Contribution to journalReview article

6 Scopus citations

Abstract

There has been sustained progress toward the identification of the gene for multiple endocrine neoplasia type 2. Closely linked and flanking DNA markers have been identified, and it is now possible to assign gene carrier status in informative families at risk with a >90% certainty by the use of molecular genetic techniques. Application of-these techniques, however, requires an understanding of their current limitations and caution in their use of clinical decision making.

Original languageEnglish (US)
Pages (from-to)19-25
Number of pages7
JournalTrends in Endocrinology and Metabolism
Volume2
Issue number1
DOIs
StatePublished - 1991

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

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