TY - JOUR
T1 - The kidney, COVID-19, and the chemokine network
T2 - an intriguing trio
AU - Taverna, Gianluigi
AU - Di Francesco, Simona
AU - Borroni, Elena Monica
AU - Yiu, Daniel
AU - Toniato, Elena
AU - Milanesi, Samantha
AU - Chiriva-Internati, Maurizio
AU - Bresalier, Robert S.
AU - Zanoni, Matteo
AU - Vota, Paolo
AU - Maffei, Davide
AU - Justich, Matteo
AU - Grizzi, Fabio
N1 - Publisher Copyright:
© 2020, Springer Nature B.V.
PY - 2021/1
Y1 - 2021/1
N2 - On December 30th 2019, some patients with pneumonia of unknown etiology were reported in the Program for Monitoring Emerging Diseases (ProMED), a program run by the International Society for Infectious Diseases (ISID), hypothesized to be related to subjects who had had contact with the seafood market in Wuhan, China. Chinese authorities instituted an emergency agency aimed at identifying the source of infection and potential biological pathogens. It was subsequently named by the World Committee on Virus Classification as 2019-nCoV (2019-novel coronavirus) or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A number of studies have demonstrated that 2019-nCoV and the SARS-CoV shared the same cell entry receptor named angiotensin-converting enzyme 2 (ACE2). This is expressed in human tissues, not only in the respiratory epithelia, but also in the small intestines, heart, liver, and kidneys. Here, we examine the most recent findings on the effects of SARS-CoV-2 infection on kidney diseases, mainly acute kidney injury, and the potential role of the chemokine network.
AB - On December 30th 2019, some patients with pneumonia of unknown etiology were reported in the Program for Monitoring Emerging Diseases (ProMED), a program run by the International Society for Infectious Diseases (ISID), hypothesized to be related to subjects who had had contact with the seafood market in Wuhan, China. Chinese authorities instituted an emergency agency aimed at identifying the source of infection and potential biological pathogens. It was subsequently named by the World Committee on Virus Classification as 2019-nCoV (2019-novel coronavirus) or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A number of studies have demonstrated that 2019-nCoV and the SARS-CoV shared the same cell entry receptor named angiotensin-converting enzyme 2 (ACE2). This is expressed in human tissues, not only in the respiratory epithelia, but also in the small intestines, heart, liver, and kidneys. Here, we examine the most recent findings on the effects of SARS-CoV-2 infection on kidney diseases, mainly acute kidney injury, and the potential role of the chemokine network.
KW - 2019-nCoV
KW - Acute kidney injury
KW - Chemokines
KW - Coronavirus
KW - Kidney
KW - SARS-CoV-2
KW - Urology
UR - http://www.scopus.com/inward/record.url?scp=85088592729&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85088592729&partnerID=8YFLogxK
U2 - 10.1007/s11255-020-02579-8
DO - 10.1007/s11255-020-02579-8
M3 - Review article
C2 - 32720031
AN - SCOPUS:85088592729
SN - 0301-1623
VL - 53
SP - 97
EP - 104
JO - International Urology and Nephrology
JF - International Urology and Nephrology
IS - 1
ER -