The meaning of 21 in the MicroRNA world: Perfection rather than destruction?

Eun Jung Jung, George A. Calin

Research output: Contribution to journalShort surveypeer-review

11 Scopus citations

Abstract

In this issue of Cancer Cell, Hatley et al., by using several tour-de-force in vivo approaches, reported a miR-21-mediated oncogenic pathway through inhibition of negative regulators of the Ras/MEK/ERK pathway and inhibition of apoptosis in lung cancers models. Targeting miR-21 could be a promising therapeutic strategy in lung cancers.

Original languageEnglish (US)
Pages (from-to)203-205
Number of pages3
JournalCancer cell
Volume18
Issue number3
DOIs
StatePublished - Sep 2010

ASJC Scopus subject areas

  • Oncology
  • Cell Biology
  • Cancer Research

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