The Metastasis Problem Gets Stickier

Lawrence N. Kwong; Lynda Chin

doi:10.1016/j.ccr.2008.12.007

The Metastasis Problem Gets Stickier

Lawrence N. Kwong, Lynda Chin

Genomic Medicine

Research output: Contribution to journal › Short survey › peer-review

13 Scopus citations

Abstract

The enormity and complexity of cancer genome data present significant challenges in downstream validation of novel oncogenes and tumor suppressors. In this issue of Cancer Cell, Hu et al. evaluate candidate oncogenes in a recurrent amplification in poor-prognosis breast cancers. They identify and validate the prometastatic gene metadherin (MTDH) as a key modulator of endothelial adhesion and chemoresistance.

Original language	English (US)
Pages (from-to)	1-2
Number of pages	2
Journal	Cancer cell
Volume	15
Issue number	1
DOIs	https://doi.org/10.1016/j.ccr.2008.12.007
State	Published - Jan 6 2009

ASJC Scopus subject areas

Oncology
Cell Biology
Cancer Research

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10.1016/j.ccr.2008.12.007

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title = "The Metastasis Problem Gets Stickier",

abstract = "The enormity and complexity of cancer genome data present significant challenges in downstream validation of novel oncogenes and tumor suppressors. In this issue of Cancer Cell, Hu et al. evaluate candidate oncogenes in a recurrent amplification in poor-prognosis breast cancers. They identify and validate the prometastatic gene metadherin (MTDH) as a key modulator of endothelial adhesion and chemoresistance.",

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AB - The enormity and complexity of cancer genome data present significant challenges in downstream validation of novel oncogenes and tumor suppressors. In this issue of Cancer Cell, Hu et al. evaluate candidate oncogenes in a recurrent amplification in poor-prognosis breast cancers. They identify and validate the prometastatic gene metadherin (MTDH) as a key modulator of endothelial adhesion and chemoresistance.

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The Metastasis Problem Gets Stickier

Abstract

ASJC Scopus subject areas

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