The Metastasis Problem Gets Stickier

Lawrence N. Kwong, Lynda Chin

Research output: Contribution to journalShort surveypeer-review

13 Scopus citations


The enormity and complexity of cancer genome data present significant challenges in downstream validation of novel oncogenes and tumor suppressors. In this issue of Cancer Cell, Hu et al. evaluate candidate oncogenes in a recurrent amplification in poor-prognosis breast cancers. They identify and validate the prometastatic gene metadherin (MTDH) as a key modulator of endothelial adhesion and chemoresistance.

Original languageEnglish (US)
Pages (from-to)1-2
Number of pages2
JournalCancer cell
Issue number1
StatePublished - Jan 6 2009

ASJC Scopus subject areas

  • Oncology
  • Cell Biology
  • Cancer Research


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