Abstract
Angiogenesis plays a vital role in tumor growth and progression. Discovering the molecular underpinnings of tumor angiogenesis has led to the development of many targeted therapies. Some of these therapies have improved patient survival, but their overall impact has been blunted by relatively modest efficacy and the eventual emergence of adaptive resistance. Developing new therapies and identifying predictive biomarkers hold a promise to improve the efficacy of anti-angiogenesis therapy.
Original language | English (US) |
---|---|
Title of host publication | Targeted Therapy in Translational Cancer Research |
Publisher | Wiley-Blackwell |
Pages | 64-71 |
Number of pages | 8 |
ISBN (Electronic) | 9781118468678 |
ISBN (Print) | 9781118468579 |
DOIs | |
State | Published - Oct 30 2015 |
Keywords
- Angiogenesis
- Biomarker
- Cancer
- Resistance
- Targeted
ASJC Scopus subject areas
- General Medicine