The Role of Angiogenesis in Cancer

Morgan Taylor, Robert L. Coleman, Anil K. Sood

Research output: Chapter in Book/Report/Conference proceedingChapter

7 Scopus citations

Abstract

Angiogenesis plays a vital role in tumor growth and progression. Discovering the molecular underpinnings of tumor angiogenesis has led to the development of many targeted therapies. Some of these therapies have improved patient survival, but their overall impact has been blunted by relatively modest efficacy and the eventual emergence of adaptive resistance. Developing new therapies and identifying predictive biomarkers hold a promise to improve the efficacy of anti-angiogenesis therapy.

Original languageEnglish (US)
Title of host publicationTargeted Therapy in Translational Cancer Research
PublisherWiley-Blackwell
Pages64-71
Number of pages8
ISBN (Electronic)9781118468678
ISBN (Print)9781118468579
DOIs
StatePublished - Oct 30 2015

Keywords

  • Angiogenesis
  • Biomarker
  • Cancer
  • Resistance
  • Targeted

ASJC Scopus subject areas

  • General Medicine

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