TY - JOUR
T1 - The Role of Vitamin D in Autoimmune Thyroid Diseases
T2 - A Narrative Review †
AU - Czarnywojtek, Agata
AU - Florek, Ewa
AU - Pietrończyk, Krzysztof
AU - Sawicka-Gutaj, Nadia
AU - Ruchała, Marek
AU - Ronen, Ohad
AU - Nixon, Iain J.
AU - Shaha, Ashok R.
AU - Rodrigo, Juan Pablo
AU - Tufano, Ralph Patrick
AU - Zafereo, Mark
AU - Randolph, Gregory William
AU - Ferlito, Alfio
N1 - Publisher Copyright:
© 2023 by the authors.
PY - 2023/2
Y1 - 2023/2
N2 - Vitamin D (VitD) deficiency has garnered significant attention in contemporary medical research. Although the canonical biological activity of VitD manifests itself mainly in the regulation of calcium-phosphorus metabolism, recent studies show that, thanks to the presence of numerous receptors, VitD may also play an important role in regulating the immune system. VitD deficiency has been demonstrated to impact autoimmune disease, coeliac disease, infections (including respiratory/COVID-19), and patients with cancer. Recent studies also show that VitD plays a significant role in autoimmune thyroid diseases (AITDs). Many studies have shown a correlation between low VitD levels and chronic autoimmune thyroiditis – Hashimoto thyroiditis (HT), Graves’ disease (GD), and postpartum thyroiditis (PPT). This review article, therefore, describes the current state of knowledge on the role of VitD in AITDs, including HT, GD, and PTT.
AB - Vitamin D (VitD) deficiency has garnered significant attention in contemporary medical research. Although the canonical biological activity of VitD manifests itself mainly in the regulation of calcium-phosphorus metabolism, recent studies show that, thanks to the presence of numerous receptors, VitD may also play an important role in regulating the immune system. VitD deficiency has been demonstrated to impact autoimmune disease, coeliac disease, infections (including respiratory/COVID-19), and patients with cancer. Recent studies also show that VitD plays a significant role in autoimmune thyroid diseases (AITDs). Many studies have shown a correlation between low VitD levels and chronic autoimmune thyroiditis – Hashimoto thyroiditis (HT), Graves’ disease (GD), and postpartum thyroiditis (PPT). This review article, therefore, describes the current state of knowledge on the role of VitD in AITDs, including HT, GD, and PTT.
KW - Graves’ disease
KW - Hashimoto thyroiditis
KW - postpartum thyroiditis
KW - Riedel thyroiditis
KW - vitamin D
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U2 - 10.3390/jcm12041452
DO - 10.3390/jcm12041452
M3 - Review article
C2 - 36835987
AN - SCOPUS:85148934355
SN - 2077-0383
VL - 12
JO - Journal of Clinical Medicine
JF - Journal of Clinical Medicine
IS - 4
M1 - 1452
ER -