The use of 18F-fluorodeoxyglucose positron emission tomography for the diagnosis and management of invasive mould infections

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Abstract

There is limited information on the utility of 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) for the diagnosis and management of invasive mould infections (IMIs). We retrospectively evaluated patients with IMIs who underwent FDG-PET in our institution (n=13; December 1999 to April 2004), and reviewed the available literature (n=9). In 16 non-neutropenic patients with available FDG-PET imaging studies (11 from our institution), FDG-PET revealed an occult IMI site (n=3; 2 unidentified CNS involvement) and was helpful in guiding the duration of treatment (n=8). Prospective evaluation of the role of FDG-PET in the work-up and management of IMIs is needed.

Original languageEnglish (US)
Pages (from-to)23-29
Number of pages7
JournalMedical mycology
Volume46
Issue number1
DOIs
StatePublished - Feb 1 2008

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Keywords

  • Aspergillus
  • Diagnosis
  • FDG-PET imaging
  • Haematological malignancies
  • Invasive mould infections
  • Zygomycetes

ASJC Scopus subject areas

  • Infectious Diseases

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