Titration of nicotine intake with full-length and half-length cigarettes

Ellen R. Gritz, Vivian Baer-Weiss, Murray E. Jarvik

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Titration, the self-regulation of nicotine intake, was studied in 12 smokers by gas chromatograph assays of urinary nicotine levels. Results demonstrated that excretion of urinary nicotine in the proximal condition (half cigarette closer to the filter) did not differ significantly.from the whole cigarette condition; however, less nicotine was excreted in the distal condition (half cigarette farther from the filter) because of a rod filtration effect. Subjects extracted proportionately more nicotine from the half than from the whole cigarettes; titration was approximately the same in both half-cigarette conditions. On scales of strength and satisfaction, full-length cigarettes were given the highest rating, followed by proximal and then distal cigarettes.

Original languageEnglish (US)
Pages (from-to)552-556
Number of pages5
JournalClinical Pharmacology and Therapeutics
Volume20
Issue number5
StatePublished - Nov 1976

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Nicotine
Tobacco Products
Gases

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

Cite this

Gritz, E. R., Baer-Weiss, V., & Jarvik, M. E. (1976). Titration of nicotine intake with full-length and half-length cigarettes. Clinical Pharmacology and Therapeutics, 20(5), 552-556.

Titration of nicotine intake with full-length and half-length cigarettes. / Gritz, Ellen R.; Baer-Weiss, Vivian; Jarvik, Murray E.

In: Clinical Pharmacology and Therapeutics, Vol. 20, No. 5, 11.1976, p. 552-556.

Research output: Contribution to journalArticle

Gritz, ER, Baer-Weiss, V & Jarvik, ME 1976, 'Titration of nicotine intake with full-length and half-length cigarettes', Clinical Pharmacology and Therapeutics, vol. 20, no. 5, pp. 552-556.
Gritz, Ellen R. ; Baer-Weiss, Vivian ; Jarvik, Murray E. / Titration of nicotine intake with full-length and half-length cigarettes. In: Clinical Pharmacology and Therapeutics. 1976 ; Vol. 20, No. 5. pp. 552-556.
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