Total Synthesis of Herquline B and C

Joshua B. Cox; Aoi Kimishima; John L. Wood

doi:10.1021/jacs.8b10212

Total Synthesis of Herquline B and C

Joshua B. Cox
, Aoi Kimishima
, John L. Wood

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

The total syntheses of (-)-herquline B (2) and a heretofore-unrecognized congener, (+)-herquline C (3), are described. The syntheses require 14 and 13 steps, respectively, and feature a key oxazoline reduction that sets the stage for piperazine construction.

Original language	English (US)
Pages (from-to)	25-28
Number of pages	4
Journal	Journal of the American Chemical Society
Volume	141
Issue number	1
DOIs	https://doi.org/10.1021/jacs.8b10212
State	Published - Jan 9 2019
Externally published	Yes

ASJC Scopus subject areas

Catalysis
General Chemistry
Biochemistry
Colloid and Surface Chemistry

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title = "Total Synthesis of Herquline B and C",

abstract = "The total syntheses of (-)-herquline B (2) and a heretofore-unrecognized congener, (+)-herquline C (3), are described. The syntheses require 14 and 13 steps, respectively, and feature a key oxazoline reduction that sets the stage for piperazine construction.",

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AU - Cox, Joshua B.

AU - Kimishima, Aoi

AU - Wood, John L.

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N2 - The total syntheses of (-)-herquline B (2) and a heretofore-unrecognized congener, (+)-herquline C (3), are described. The syntheses require 14 and 13 steps, respectively, and feature a key oxazoline reduction that sets the stage for piperazine construction.

AB - The total syntheses of (-)-herquline B (2) and a heretofore-unrecognized congener, (+)-herquline C (3), are described. The syntheses require 14 and 13 steps, respectively, and feature a key oxazoline reduction that sets the stage for piperazine construction.

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U2 - 10.1021/jacs.8b10212

DO - 10.1021/jacs.8b10212

M3 - Article

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AN - SCOPUS:85059864825

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EP - 28

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

IS - 1

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Total Synthesis of Herquline B and C

Abstract

ASJC Scopus subject areas

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